Evidence map›Paper›PMID 25717397›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science2014

Use of RxNorm and NDF-RT to normalize and characterize participant-reported medications in an i2b2-based research repository.

Colette Blach, Guilherme Del Fiol, Chandel Dundee, Julie Frund, Rachel Richesson, Michelle Smerek, Anita Walden, Jessica D Tenenbaum

Open access · greenAbstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Colette BlachDuke University, Durham, NC.
Guilherme Del FiolUniverity of Utah, Salt Lake City, UT.
Chandel DundeeDuke University, Durham, NC.
Julie FrundDuke University, Durham, NC.
Rachel RichessonDuke University, Durham, NC.
Michelle SmerekDuke University, Durham, NC.
Anita WaldenDuke University, Durham, NC.
Jessica D TenenbaumDuke University, Durham, NC.
Duke University · US

Funding

Pilot Project for the DTMI CRA ProgramUL1RR024128 · NCRR · DUKE UNIVERSITY · PI CALIFF, ROBERT M · 2006 to 2010
$48.1M
UNIVERSITY OF UTAH MEDICAL INFORMATICS TRAININGT15LM007124 · NLM · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Karen Louise Eilbeck · 1997 to 2026
$22.0M
NCRR NIH HHS UL1 RR024128NLM NIH HHS T15 LM007124
6 · The paper itself

Abstract

The MURDOCK Study is longitudinal, large-scale epidemiological study for which participants' medication use is collected as free text. In order to maximize utility of drug data, while minimizing cost due to manual expert intervention, we have developed a generalizable approach to automatically coding medication data using RxNorm and NDF-RT and their associated application program interfaces (APIs). Of 130,273 entries, we were able to accurately map 122,523 (94%) to RxNorm concepts, and 106,135 (85%) of those drug concepts to nodes under the Drug by VA Class branch of NDF-RT. This approach has enabled use of drug data in combination with other complementary information for cohort identification within an i2b2-based participant registry. The method may be generalized to other projects requiring coding of medication data from free-text.

Identifiers

PMID25717397
PMCPMC4333688
OpenAlexW108665436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.