Evidence map›Paper›PMID 25717147›Full record

ArticleJournal of leukocyte biology2015

Prostaglandins produced during class A scavenger receptor-mediated macrophage adhesion differentially regulate cytokine production.

Dejan M Nikolic, Shanthi Vadali, Beixiang He, Jerry Ware, Thomas Kelly, Steven R Post

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of leukocyte biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dejan M NikolicDepartments of *Pathology, Pharmacology and Toxicology, and Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Shanthi VadaliDepartments of *Pathology, Pharmacology and Toxicology, and Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Beixiang HeDepartments of *Pathology, Pharmacology and Toxicology, and Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Jerry WareDepartments of *Pathology, Pharmacology and Toxicology, and Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Thomas KellyDepartments of *Pathology, Pharmacology and Toxicology, and Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Steven R PostDepartments of *Pathology, Pharmacology and Toxicology, and Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA spost@uams.edu.
University of Arkansas for Medical Sciences · US

Funding

Function and Regulation of SR-A in AtherosclerosisR01HL089588 · NHLBI · UNIV OF ARKANSAS FOR MED SCIS · PI POST, STEVEN · 2008 to 2011
$1.4M
NHLBI NIH HHS R01 HL089588
6 · The paper itself

Abstract

Inflammation is associated with modification of the extracellular environment, changes in cytokine expression, and the accumulation of immune cells. Such modifications create ligands that support SR-A-mediated macrophage adhesion and retention. This may be particularly important in settings, such as atherosclerosis and diabetes, as modified lipoproteins and gluc-collagen are ligands for SR-A. SR-A-mediated adhesion requires the PLA

Indexed as

cyclooxygenaseinflammationPGE2phospholipase A2

Identifiers

PMID25717147
PMCPMC8454924
OpenAlexW2024586196

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.