Evidence map›Paper›PMID 25717004›Full record

ReviewJournal of cell science2015

An active role for basement membrane assembly and modification in tissue sculpting.

Meghan A Morrissey, David R Sherwood

Abstract readReview
In one paragraph

Review in Journal of cell science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. The life cycle of type IV collagen.Matrix biology : journal of the International Society for Matrix Biology · 2025
    Review
  5. Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  6. iScience · 2025
    Article
  7. Article
  8. Article
  9. Basement membrane patterning by spatial deployment of a secretion-regulating protease.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Mechanisms of assembly and remodelling of the extracellular matrix.Nature reviews. Molecular cell biology · 2024
    Review
  17. Review
  18. Article
  19. Article
  20. Kidney resident macrophages have distinct subsets and multifunctional roles.Matrix biology : journal of the International Society for Matrix Biology · 2024
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Meghan A MorrisseyDepartment of Biology, Duke University, Science Drive, Box 90388, Durham, NC 27708, USA.
David R SherwoodDepartment of Biology, Duke University, Science Drive, Box 90388, Durham, NC 27708, USA david.sherwood@duke.edu.

Funding

Genetic Analysis of Cell Invasion through Basement MembranesR01GM079320 · NIGMS · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2007 to 2015
$2.8M
Understanding How Invadosomes Breach Basement Membrane In VivoR01GM100083 · NIGMS · DUKE UNIVERSITY · PI SHERWOOD, DAVID R · 2012 to 2015
$1.1M
NIGMS NIH HHS GM079320NIGMS NIH HHS GM100083NIGMS NIH HHS R01 GM079320NIGMS NIH HHS R01 GM100083
6 · The paper itself

Abstract

Basement membranes are a dense, sheet-like form of extracellular matrix (ECM) that underlie epithelia and endothelia, and surround muscle, fat and Schwann cells. Basement membranes separate tissues and protect them from mechanical stress. Although traditionally thought of as a static support structure, a growing body of evidence suggests that dynamic basement membrane deposition and modification instructs coordinated cellular behaviors and acts mechanically to sculpt tissues. In this Commentary, we highlight recent studies that support the idea that far from being a passive matrix, basement membranes play formative roles in shaping tissues.

Indexed as

Organ SpecificityAnimalsBasement MembraneCell PolarityCollagenHumansModels, BiologicalCollagen

Identifiers

PMID25717004
PMCPMC4446735

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.