Evidence map›Paper›PMID 25716828›Full record

ArticleGenome biology and evolution2015

Genome sequence, comparative analysis, and evolutionary insights into chitinases of entomopathogenic fungus Hirsutella thompsonii.

Yamini Agrawal, Indu Khatri, Srikrishna Subramanian, Belle Damodara Shenoy

Open access · goldAbstract readComparative Study
In one paragraph

Article in Genome biology and evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 45 citations in OpenAlex.

  1. mBio · 2025
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  2. A Genomic Sequence Resource ofJournal of fungi (Basel, Switzerland) · 2024
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  7. Phylogeny and Systematics of the GenusJournal of fungi (Basel, Switzerland) · 2022
    Article
  8. Article
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  11. Open biology · 2020
    Review
  12. Review
  13. Genome Analysis ofGenes · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. The Insect Pathogens.Microbiology spectrum · 2017
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Yamini AgrawalCSIR-Institute of Microbial Technology, Chandigarh, India.
Indu KhatriCSIR-Institute of Microbial Technology, Chandigarh, India.
Srikrishna SubramanianCSIR-Institute of Microbial Technology, Chandigarh, India krishna@imtech.res.in shenoynio@gmail.com.
Belle Damodara ShenoyCSIR-Institute of Microbial Technology, Chandigarh, India Present address: CSIR-National Institute of Oceanography, Dona Paula, Goa, India krishna@imtech.res.in shenoynio@gmail.com.
Council of Scientific and Industrial Research · INInstitute of Microbial Technology · INNational Institute of Oceanography · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hirsutella thompsonii (Ht) is a fungal pathogen of acarines and the primary cause of epizootics among mites. The draft genomes of two isolates of Ht (MTCC 3556: Ht3, 34.6 Mb and MTCC 6686: Ht6, 34.7 Mb) are presented and compared with the genomes of Beauveria bassiana (Bb) ARSEF 2860 and Ophiocordyceps sinensis (Os) CO18. Comparative analysis of carbohydrate active enzymes, pathogen-host interaction genes, metabolism-associated genes, and genes involved in biosynthesis of secondary metabolites in the four genomes was carried out. Reduction in gene family sizes in Ht3 and Os as compared with Ht6 and Bb is observed. Analysis of the mating type genes in Ht reveals the presence of MAT idiomorphs which is suggestive of cryptic sexual traits in Ht. We further identify and classify putative chitinases that may function as virulence factors in fungal entomopathogens due to their role in degradation of arthropod cuticle.

Indexed as

Evolution, MolecularGenome, FungalBeauveriaCarbohydrate MetabolismChitinasesDNA Transposable ElementsGenomicsHost-Pathogen InteractionsHypocrealesMultigene FamilyPhylogenyProtein Structure, TertiarySecondary MetabolismChitinasesDNA Transposable Elementsglycoside hydrolase family 18mycoinsecticidepathogen–host interactionsphylogenetic classificationsubgroups A, B, and C

Identifiers

PMID25716828
PMCPMC5322555
OpenAlexW2117980392

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.