ArticleJournal of clinical microbiology2015
Acrophialophora, a poorly known fungus with clinical significance.
Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Genome analysis of Acrophialophora yunnanensis and its lignocellulolytic enzyme system.World journal of microbiology & biotechnology · 2026Article
- Uncharted Territory.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Expanding Epidemiology: A Case of Pulmonary Disease Caused byOpen forum infectious diseases · 2025Article
- Refractory Fungal Keratitis Caused by Acrophialophora fusispora: A Case Report and Literature Review.Cureus · 2023Article
- A surgeon's trial success of curing pedal eumycetoma.BMJ case reports · 2023Article
- Taxonomy and Phylogeny of Eight NewJournal of fungi (Basel, Switzerland) · 2023Article
- Review
- Article
- Article
- The first case of Acrophialophora levis-induced severe pneumonia: a case report and literature review.BMC infectious diseases · 2019Article
- Diversity of Endophytic Fungi of the Coastal Plant Vitex rotundifolia in Taiwan.Microbes and environments · 2019Article
- Humicola sp. as a Cause of Peritoneal Dialysis-Associated Peritonitis.Journal of clinical microbiology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acrophialophora fusispora is an emerging opportunistic fungus capable of causing human infections. The taxonomy of the genus is not yet resolved and, in order to facilitate identification of clinical specimens, we have studied a set of clinical and environmental Acrophialophora isolates by morphological and molecular analyses. This set included the available type strains of Acrophialophora species and similar fungi, some of which were considered by various authors to be synonyms of A. fusispora. Sequence analysis of the large subunit (LSU) and internal transcribed spacer (ITS) regions of the nuclear ribosomal DNA and a fragment of the β-tubulin (Tub) gene revealed that Acrophialophora belongs in the family Chaetomiaceae and comprises three different species, i.e., A. fusispora, Acrophialophora levis, and Acrophialophora seudatica; the latter was previously included in the genus Ampullifera. The most prevalent species among clinical isolates was A. levis (72.7%), followed by A. fusispora (27.3%), both of which were isolated mostly from respiratory specimens (72.7%), as well as subcutaneous and corneal tissue samples. In general, of the eight antifungal drugs tested, voriconazole had the greatest in vitro activity, while all other agents showed poor in vitro activity against these fungi.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.