Evidence map›Paper›PMID 25716016›Full record

SynthesisExperimental biology and medicine (Maywood, N.J.)2015

Far-infrared therapy for cardiovascular, autoimmune, and other chronic health problems: A systematic review.

Shanshan Shui, Xia Wang, John Y Chiang, Lei Zheng

Retracted 2 registry-linked trialsOpen access · greenAbstract readSystematic ReviewRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Experimental biology and medicine (Maywood, N.J.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04011072 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Far Infrared Therapy on Arteriovenous Fistulas Maturation, Survival and Stenosis. A Randomized, Controlled Open-labeled Multicenter Study

TypeinterventionalSponsorHerlev and Gentofte HospitalRan2019 to 2023Enrolled206ConditionsArterio-venous FistulaArmsFar infrared radiation
NCT04460612 nacompletednot on this mapstarted 2021, after this paper: background citation

A Pilot Study of the Impact of Passive, Garment-based Infrared Therapy on Oxygenation in the Feet and Lower Legs of Patients With Diabetes

TypeinterventionalSponsorYale UniversityRan2021 to 2022Enrolled39ConditionsDiabetesArmsActive IR sock, Placebo socks
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 64 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Far-infrared radiation stimulates platelet-derived growth factor mediated skeletal muscle cell migration through extracellular matrix-integrin signaling.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2019
    Article
  14. Article
  15. Review
  16. Article
  17. Clinical Effects of Regular Dry Sauna Bathing: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2018
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Shanshan ShuiSchool of Medical Engineering, Hefei University of Technology, Hefei 230009, China School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei 230009, China.
Xia WangSchool of Medical Engineering, Hefei University of Technology, Hefei 230009, China.
John Y ChiangDepartment of Computer Science & Engineering, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan Department of Healthcare Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung 80708, Taiwan lzheng@hfut.edu.cn chiang@cse.nsysu.edu.tw.
Lei ZhengSchool of Medical Engineering, Hefei University of Technology, Hefei 230009, China School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei 230009, China lzheng@hfut.edu.cn chiang@cse.nsysu.edu.tw.
Hefei University of Technology · CNKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical therapy (physiotherapy), a complementary and alternative medicine therapy, has been widely applied in diagnosing and treating various diseases and defects. Increasing evidence suggests that convenient and non-invasive far-infrared (FIR) rays, a vital type of physiotherapy, improve the health of patients with cardiovascular disease, diabetes mellitus, and chronic kidney disease. Nevertheless, the molecular mechanisms by which FIR functions remain elusive. Hence, the purpose of this study was to review and summarize the results of previous investigations and to elaborate on the molecular mechanisms of FIR therapy in various types of disease. In conclusion, FIR therapy may be closely related to the increased expression of endothelial nitric oxide synthase as well as nitric oxide production and may modulate the profiles of some circulating miRNAs; thus, it may be a beneficial complement to treatments for some chronic diseases that yields no adverse effects.

Indexed as

PhototherapyCardiovascular DiseasesDiabetes MellitusHumansIschemiaModels, BiologicalNitric Oxide Synthase Type IIIRenal Insufficiency, ChronicNitric Oxide Synthase Type IIIcardiovascular disease (CVD)diabetes mellitus (DM)far-infrared (FIR)miRNAPhysical therapy

Identifiers

PMID25716016
PMCPMC4935255
OpenAlexW2094278351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.