Evidence map›Paper›PMID 25715916›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2015

Biomarkers in electrophysiology: role in arrhythmias and resynchronization therapy.

Abhishek Bose, Quynh A Truong, Jagmeet P Singh

Abstract read
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abhishek BoseCardiac Arrhythmia Service, Cardiology Division, Massachusetts General Hospital Heart Center, 55 Fruit Street, Boston, MA, 02114, USA.
Quynh A Truong
Jagmeet P Singh

Funding

Computed Tomography to Predict Response to Cardiac Resynchronization TherapyK23HL098370 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI TRUONG, QUYNH A. · 2010 to 2014
$816k
NHLBI NIH HHS K23 HL098370NHLBI NIH HHS K23HL098370NHLBI NIH HHS L30 HL093806NHLBI NIH HHS L30HL093896
6 · The paper itself

Abstract

Circulating biomarkers related to inflammation, neurohormones, myocardial stress, and necrosis have been associated with commonly encountered arrhythmic disorders such as atrial fibrillation (AF) and more malignant processes including ventricular arrhythmias (VA) and sudden cardiac death (SCD). Both direct and indirect biomarkers implicated in the heart failure cascade have potential prognostic value in patients undergoing cardiac resynchronization therapy (CRT). This review will focus on the role of biomarkers in AF, history of SCD, and CRT with an emphasis to improve clinical risk assessment for arrhythmias and patient selection for device therapy. Notably, information obtained from biomarkers may supplement traditional diagnostic and imaging techniques, thus providing an additional benefit in the management of patients.

Indexed as

Patient SelectionArrhythmias, CardiacBiomarkersCardiac Resynchronization TherapyCytokinesEvidence-Based MedicineHumansPrognosisReproducibility of ResultsRisk AssessmentSensitivity and SpecificityTreatment OutcomeBiomarkersCytokines

Identifiers

PMID25715916
PMCPMC4487609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.