ReviewCellular and molecular life sciences : CMLS2015
Eukaryotic enhancers: common features, regulation, and participation in diseases.
Review in Cellular and molecular life sciences : CMLS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Enhancers integrate microenvironmental signals in muscle stem cells during regeneration in health, disease, and aging.Skeletal muscle · 2026Review
- Configuring the Code: Enhancer-Promoter Arrangement and Transcriptional Regulation.Journal of molecular biology · 2026Review
- Epigenetic Regulation in Drosophila Tumor Models.Advances in experimental medicine and biology · 2025Review
- Exploring the Role of Enhancer-Mediated Transcriptional Regulation in Precision Biology.International journal of molecular sciences · 2023Review
- The Non-Specific Lethal (NSL) Histone Acetyltransferase Complex Transcriptionally Regulates Yin Yang 1-Mediated Cell Proliferation in Human Cells.International journal of molecular sciences · 2022Article
- Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases.International journal of molecular sciences · 2021Review
- Systematic analysis of enhancer regulatory circuit perturbation driven by copy number variations in malignant glioma.Theranostics · 2021Article
- Evolution of Regulated Transcription.Cells · 2020Review
- Innovative Molecular Testing Strategies for Adjunctive Investigations in Hemostasis and Thrombosis.Seminars in thrombosis and hemostasis · 2019Review
- Effect of Transcription on the white Gene Enhancer Integrated into the Intron.Doklady. Biochemistry and biophysics · 2019Article
- The Role of GC-Rich Sequences from the Promoter Region of the Drosophila melanogaster yellow Gene in the Enhancer- Dependent Activation of Transcription.Doklady. Biochemistry and biophysics · 2018Article
- Development of a computational promoter with highly efficient expression in tumors.BMC cancer · 2018Article
- Characterization of enhancers and the role of the transcription factor KLF7 in regulating corneal epithelial differentiation.The Journal of biological chemistry · 2017Article
- Regular Higher Order Repeat Structures in Beetle Tribolium castaneum Genome.Genome biology and evolution · 2017Article
- GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states.PLoS genetics · 2017Article
- The bxdPRE/TRE element terminates passing through transcription.Doklady. Biochemistry and biophysics · 2017Article
- An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility.Biological psychiatry · 2016Article
- Review
- In silico identification of enhancers on the basis of a combination of transcription factor binding motif occurrences.Scientific reports · 2016Article
- Brachyury, Foxa2 and the cis-Regulatory Origins of the Notochord.PLoS genetics · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enhancers are positive DNA regulatory sequences controlling temporal and tissue-specific gene expression. These elements act independently of their orientation and distance relative to the promoters of target genes. Enhancers act through a variety of transcription factors that ensure their correct match with target promoters and consequent gene activation. There is a growing body of evidence on association of enhancers with transcription factors, co-activators, histone chromatin marks, and lncRNAs. Alterations in enhancers lead to misregulation of gene expression, causing a number of human diseases. In this review, we focus on the common characteristics of enhancers required for transcription stimulation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.