Evidence map›Paper›PMID 25715096›Full record

ReviewHuman vaccines & immunotherapeutics2015

Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part II: Vaccines for Shigella, Salmonella, enterotoxigenic E. coli (ETEC) enterohemorragic E. coli (EHEC) and Campylobacter jejuni.

Miguel O'Ryan, Roberto Vidal, Felipe del Canto, Juan Carlos Salazar, David Montero

Open access · bronzeAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 57 citations in OpenAlex.

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  4. Optimization ofJournal of environmental engineering (New York, N.Y.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Miguel O'Ryana Microbiology and Mycology Program; Institute of Biomedical Sciences; Faculty of Medicine; Universidad de Chile; Santiago, Chile.
Roberto Vidal
Felipe del Canto
Juan Carlos Salazar
David Montero
Faculty (United Kingdom) · GBUniversidad de Santiago de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Part II we discuss the following bacterial pathogens: Shigella, Salmonella (non-typhoidal), diarrheogenic E. coli (enterotoxigenic and enterohemorragic) and Campylobacter jejuni. In contrast to the enteric viruses and Vibrio cholerae discussed in Part I of this series, for the bacterial pathogens described here there is only one licensed vaccine, developed primarily for Vibrio cholerae and which provides moderate protection against enterotoxigenic E. coli (ETEC) (Dukoral(®)), as well as a few additional candidates in advanced stages of development for ETEC and one candidate for Shigella spp. Numerous vaccine candidates in earlier stages of development are discussed.

Indexed as

Bacterial VaccinesCampylobacter jejuniClinical Trials as TopicDiarrheaDrug ApprovalDrug DiscoveryDrug Evaluation, PreclinicalEscherichia coliGastroenteritisHumansSalmonellaShigellaBacterial Vaccinesacute diarrheaCampylobacterCFs, colonization factorsCFU, colony-forming unitsCT-B cholera toxin B subunitCT, cholera toxinCtdB, cytolethal distending toxin subunit BdmLT, double mutant heat labile toxinE. coliEHECenteric pathogensenterohemorrhagic E. coliEPEC, enteropathogenic E. coliETECETEC, enterotoxigenic E. coligastroenteritisGEMS, Global enterics multicenter studyheat labile toxin B subunitHUS, hemolytic uremic syndromeIgA, immunoglobulin AIgG, immunoglobulin GIgM, immunoglobulin MIM, intramuscularLEE, locus of enterocyte effacementLPS, lipopolysaccharideLT-BLT, heat labile toxinnorovirusOMV, outer membrane vesiclesrEPA, recombinant exoprotein A of Pseudomonas aeruginosarotavirusSalmonellaShigellaSTECSTEC, shigatoxin producing E. coliST, heat stable toxinSTh, human heat stable toxinSTp, porcine heat stable toxinStx, shigatoxinTTSS, type III secretion systemvaccinesV. choleraWHO, World Health Organization

Identifiers

PMID25715096
PMCPMC4514228
OpenAlexW1820901512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.