Evidence map›Paper›PMID 25714581›Full record

ArticleJournal of pediatric gastroenterology and nutrition2015

Comparison of WHO and CDC growth charts in predicting pulmonary outcomes in cystic fibrosis.

Evans Machogu, Yumei Cao, Tami Miller, Pippa Simpson, Hara Levy, Diana Quintero, Praveen S Goday

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Short Stature Diagnosis and Referral.Frontiers in endocrinology · 2017
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Evans Machogu*Division of Pediatric Pulmonology, Medical College of Wisconsin †Quantitative Health Sciences ‡Cystic Fibrosis Program, Children's Hospital of Wisconsin ||Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Medical College of Wisconsin, Milwaukee, WI.
Yumei Cao
Tami Miller
Pippa Simpson
Hara Levy
Diana Quintero
Praveen S Goday
Medical College of Wisconsin · USChildren's Hospital of Wisconsin · US

Funding

Integration of Genomics with Genetics - Molecular Phenotypes for CF Lung DiseaseDP2OD007031 · OD · MEDICAL COLLEGE OF WISCONSIN · PI LEVY, HARA · 2010 to 2010
$2.2M
NIH HHS DP2 OD007031
6 · The paper itself

Abstract

objectivesThe relation of weight-for-length (WFL) and weight-for-age (WFA) measurements with pulmonary function in patients with cystic fibrosis (CF) using the World Health Organization (WHO) growth standards has not been evaluated. The objective of the present study was to show that the relation of WFL and WFA measurements at 2 years with forced expiratory volume in 1 second (FEV1) at 6 to 8 years differs when using the WHO versus the Centers for Disease Control and Prevention (CDC) growth charts.

methodsWe assessed 1155 patients in the CF Foundation Patient Registry born between 2001 and 2004. Comparisons were made between the CDC and WHO growth charts.

resultsThe WFL percentiles are significantly higher for the WHO growth standards compared with those for the CDC growth charts (median and interquartile range [IQR] WHO--64.8 [41.7-84.9], CDC--48.1 [23.7-75.7], P < 0.0001). WFL and WFA percentiles at 2 years on both charts are strongly associated with FEV1 at 6 to 8 years of age. The FEV1 at 6 to 8 years was statistically significantly lower for children who were classified as reaching a WFL ≥ 50 th percentile at 2 years by WHO standards alone versus those who qualified by both growth charts (median and IQR 103 [94-115] vs 107 [96-117], P < 0.05). Continued weight gain between 2 and 6 years was associated with a higher lung function at age 6 to 8 years.

conclusionsAlthough children attaining the 50th WFL percentile on the WHO growth chart by age 2 years have a lower FEV1 at 6 years than children attaining the same percentile on the CDC chart, both groups of children attain clinically normal FEV1. Further studies are needed to determine whether this difference is clinically meaningful.

Indexed as

Child DevelopmentGrowth ChartsModels, BiologicalCenters for Disease Control and Prevention, U.S.Child Nutritional Physiological PhenomenaChild Nutrition DisordersChild, PreschoolCohort StudiesCombined Modality TherapyCystic FibrosisFemaleForced Expiratory VolumeHumansLungMaleRegistries

Identifiers

PMID25714581
PMCPMC4469983
OpenAlexW1988209871

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.