Evidence map›Paper›PMID 25714264›Full record

ReviewVirulence2015

The role of pattern recognition receptors in the innate recognition of Candida albicans.

Nan-Xin Zheng, Yan Wang, Dan-Dan Hu, Lan Yan, Yuan-Ying Jiang

Open access · goldAbstract readReview
In one paragraph

Review in Virulence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Loss of Fgr41 inInfection and immunity · 2026
    Article
  4. Article
  5. The pathogenicity and future treatment strategies ofFrontiers in cellular and infection microbiology · 2026
    Review
  6. Review
  7. Candida albicans: the current status regarding vaginal infections.Applied microbiology and biotechnology · 2025
    Review
  8. ControllingInfection and immunity · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. A Putative Role ofMicroorganisms · 2023
    Review
  13. The Interplay betweenMicroorganisms · 2023
    Review
  14. Review
  15. Article
  16. The Role of IL-17-Producing Cells in Cutaneous Fungal Infections.International journal of molecular sciences · 2021
    Review
  17. Review
  18. Kruppel-like factor 6 promotes macrophage inflammatory and hypoxia response.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  19. UpregulatedAnnals of translational medicine · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nan-Xin Zhenga Changzheng Hospital ; Second Military Medical University ; Shanghai , China.
Yan Wang
Dan-Dan Hu
Lan Yan
Yuan-Ying Jiang
Second Military Medical University · CNInternational Drug Development · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida albicans is both a commensal microorganism in healthy individuals and a major fungal pathogen causing high mortality in immunocompromised patients. Yeast-hypha morphological transition is a well known virulence trait of C. albicans. Host innate immunity to C. albicans critically requires pattern recognition receptors (PRRs). In this review, we summarize the PRRs involved in the recognition of C. albicans in epithelial cells, endothelial cells, and phagocytic cells separately. We figure out the differential recognition of yeasts and hyphae, the findings on PRR-deficient mice, and the discoveries on human PRR-related single nucleotide polymorphisms (SNPs).

Indexed as

Host-Pathogen InteractionsAnimalsCandida albicansDendritic CellsEndothelial CellsEpithelial CellsHumansHyphaeImmunity, InnateMicePhagocytesPolymorphism, Single NucleotideReceptors, Pattern RecognitionReceptors, Pattern RecognitionCandida albicansepithelial cellsinnate immunitypattern recognition receptorsphagocytic cells

Identifiers

PMID25714264
PMCPMC4601294
OpenAlexW1905566923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.