Evidence map›Paper›PMID 25713776›Full record

ReviewGland surgery2015

Loss of signal in recurrent nerve neuromonitoring: causes and management.

Che-Wei Wu, Mei-Hui Wang, Cheng-Chien Chen, Hui-Chun Chen, Hsiu-Ya Chen, Jing-Yi Yu, Pi-Ying Chang, I-Cheng Lu, Yi-Chu Lin, Feng-Yu Chiang

Abstract readReview
In one paragraph

Review in Gland surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Che-Wei Wu1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Mei-Hui Wang1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Cheng-Chien Chen1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Hui-Chun Chen1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Hsiu-Ya Chen1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Jing-Yi Yu1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Pi-Ying Chang1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
I-Cheng Lu1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Yi-Chu Lin1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.
Feng-Yu Chiang1 Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Medical University Hospital, 2 Faculty of Medicine, College of Medicine, 3 Department of Nursing, 4 Department of Anesthesiology, Kaohsiung Medical University Hospital, 5 Graduate Institute of Clinical Medicine, Graduate Institute of Medicine, 6 Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University (KMU), Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During recurrent laryngeal nerve (RLN) neuromonitoring in thyroid surgery, laryngeal electromyography (EMG) amplitude may be correlated with the number of muscle fibers participating in the polarization and these might be correlated with the function of RLN. If RLN is severely injured during the operation, most nerve fibers do not transmit nerve impulse and substantial decrease of EMG amplitude or loss of signal (LOS) will occur. True LOS at the end of an operation often indicates a postoperative fixed vocal cord, and the surgeon should consider the optimal contralateral surgery timing in patients with planned bilateral thyroid operation to avoid the disaster of bilateral vocal cord palsy. However, LOS recovery and false LOS may occur and may lead to an unnecessary 2(nd) operation. Therefore, a reliable modality for intraoperative LOS evaluation and management would afford the surgeon real-time information that could help guide surgical procedure and planning. The updated causes, algorithm, and management of LOS during RLN neuromonitoring are reviewed and summarized.

Indexed as

electromyography (EMG)intraoperative neuromonitoring (IONM)loss of signal (LOS)Recurrent laryngeal nerve (RLN)thyroid surgeryvocal cord palsy

Identifiers

PMID25713776
PMCPMC4321049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.