ArticleJournal of medicine and life
Dispersion of ventricular repolarization in relation to cardiovascular risk factors in hypertension.
Article in Journal of medicine and life. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Assessment of Hypertension Using Clinical Electrocardiogram Features: A First-Ever Review.Frontiers in medicine · 2020Pooled it
- Autonomic activity and cardiovascular system risk assessment in pediatric patients with hemolytic uremic syndrome.European journal of pediatrics · 2024Article
- T-Wave Indices and Atherosclerosis.Current atherosclerosis reports · 2018Review
- [Changes in electrocardiographic parameters in children with complete left bundle branch block early after transcatheter closure of ventricular septal defect].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleHypertension associates with sudden cardiac death, its relationship with ventricular arrhythmias being demonstrated by multiple studies, an increased dispersion of repolarization being an important arrhythmogenesis mechanism. Only a small percentage of hypertensive patients presents increased blood pressure values exclusively as risk factor, most of them presenting additional risk factors that reinforce each other leading to increased total cardiovascular risk.
aimto analyze the dispersion of repolarization parameters (QT interval, QT dispersion, Tpeak-Tend interval (Tpe), Tpe/QT, Tpe dispersion) in relation to cardiovascular risk factors, as well as total cardiovascular risk estimated by SCORE model, in mild to moderate essential hypertension.
method62 consecutive patients, mean age 55±11 years, were evaluated by 24 hours Holter electrocardiography monitoring. Manual measurement of dispersion of repolarization parameters was performed.
resultsBased on SCORE model, 33.9% patients presented low risk, 40.3% moderate risk, 16.1% high risk and 9.1% very high risk. Age had a positive correlation with QT and reverse correlations with QT dispersion, Tpe and Tpe/QT in lead V1. Tpe/QT showed significantly higher values in men versus women. Glucose metabolism disorders associated with higher values of QT and Tpe dispersion were present. However, dispersion of repolarization parameters was similar between risk categories assessed by SCORE model, Tpe in lead V3 correlated significantly with SCORE score.
conclusionsIn mild to moderate hypertension, the dispersion of repolarization parameters is influenced by age, gender and glucose metabolism disorders. Among these, Tpe in lead V3 correlates with total cardiovascular risk assessed by SCORE model.
Indexed as
Identifiers
25713619PMC4316136W223514196What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.