ArticleEuropean journal of dentistry
Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis.
Article in European journal of dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Autogenous platelet concentrates for treatment of intrabony defects-A systematic review with meta-analysis.Periodontology 2000 · 2025Pooled it
- Regeneration of periodontal intrabony defects using platelet-rich fibrin (PRF): a systematic review and network meta-analysis.Odontology · 2024Pooled it
- Use of platelet-rich fibrin for the treatment of periodontal intrabony defects: a systematic review and meta-analysis.Clinical oral investigations · 2021Pooled it
- Additive effectiveness of autologous platelet-rich fibrin in the treatment of intrabony defects: A PRISMA-compliant meta-analysis.Medicine · 2019Pooled it
- Regenerative potential of leucocyte- and platelet-rich fibrin. Part A: intra-bony defects, furcation defects and periodontal plastic surgery. A systematic review and meta-analysis.Journal of clinical periodontology · 2017Pooled it
- Clinical and radiographic effects of ascorbic acid-augmented platelet-rich fibrin versus platelet-rich fibrin alone in intra-osseous defects of stage-III periodontitis patients: a randomized controlled clinical trial.Clinical oral investigations · 2021Trial
- Comparative Evaluation of AmnioGuard and Advanced Platelet-Rich Fibrin When Combined With NovaBone Putty in the Regeneration of Human Periodontal Infrabony Defects: Protocol for a Randomized Controlled Clinical Trial.JMIR research protocols · 2026Article
- Management of intra-bony defects using nano HA+PRF over its combination with a diode laser.Bioinformation · 2025Article
- Plasma Rich in Growth Factors Compared to Xenogenic Bone Graft in Treatment of Periodontal Intra-Osseous Defects-A Prospective, Comparative Clinical Study.Journal of functional biomaterials · 2024Article
- Quantitative Association of Platelet-Rich Fibrin (PRF) and Hyperacute Serum (HAS) with Glycemic Control (HbA1c) in Chronic Periodontitis Patients: An Ex vivo Study.Journal of pharmacy & bioallied sciences · 2023Article
- Recent advances in decellularized biomaterials for wound healing.Materials today. Bio · 2023Review
- Clinical Efficacy of Platelet Derivatives in Periodontal Tissue Regeneration: An Umbrella Review.International journal of dentistry · 2023Review
- Effect of Injectable Platelet-Rich Fibrin with a Nano-Hydroxyapatite Bone Graft on the Treatment of a Grade II Furcation Defect.Bioengineering (Basel, Switzerland) · 2022Article
- Emerging roles of platelet concentrates and platelet-derived extracellular vesicles in regenerative periodontology and implant dentistry.APL bioengineering · 2022Review
- Effectiveness of Platelet-Rich Fibrin in the Treatment of Intrabony Defects with or Without Bone Graft: A Clinical Comparative Study.Journal of pharmacy & bioallied sciences · 2021Article
- Biomimetic Aspects of Restorative Dentistry Biomaterials.Biomimetics (Basel, Switzerland) · 2020Review
- Periodontal Ligament Cell Sheets and RGD-Modified Chitosan Improved Regeneration in the Horizontal Periodontal Defect Model.European journal of dentistry · 2020Article
- Evaluation of titanium-prepared platelet-rich fibrin and leucocyte platelet-rich fibrin in the treatment of intra-bony defects: A randomized clinical trial.Journal of dental research, dental clinics, dental prospects · 2020Article
- Systematic Comparison of the Effect of Four Clinical-Grade Platelet Rich Hemoderivatives on Osteoblast Behaviour.International journal of molecular sciences · 2019Article
- Comparison of Connective Tissue Graft and Platelet Rich Fibrin as Matrices in A Novel Papillary Augmentation Access: A Randomized Controlled Clinical Trial.European journal of dentistry · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe primary objective of this study was to compare clinically and radiographically the efficacy of autologous platelet rich fibrin (PRF) and autogenous bone graft (ABG) obtained using bone scrapper in the treatment of intrabony periodontal defects. MATERIALS AND
methodsThirty-eight intrabony defects (IBDs) were treated with either open flap debridement (OFD) with PRF or OFD with ABG. Clinical parameters were recorded at baseline and 6 months postoperatively. The defect-fill and defect resolution at baseline and 6 months were calculated radiographically (intraoral periapical radiographs [IOPA] and orthopantomogram [OPG]).
resultsSignificant probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, defect fill and defect resolution at both PRF and ABG treated sites with OFD was observed. However, inter-group comparison was non-significant (P > 0.05). The bivariate correlation results revealed that any of the two radiographic techniques (IOPA and OPG) can be used for analysis of the regenerative therapy in IBDs.
conclusionThe use of either PRF or ABG were effective in the treatment of three wall IBDs with an uneventful healing of the sites.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.