Evidence map›Paper›PMID 25713486›Full record

ArticleEuropean journal of dentistry

Crevicular fluid levels of interleukin-8, interleukin-17 and soluble intercellular adhesion molecule-1 after regenerative periodontal therapy.

Ebru Olgun Erdemir, Meltem Karsiyaka Hendek, H Gencay Keceli, Teoman Z Apan

Abstract read
In one paragraph

Article in European journal of dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Article
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  5. Article
  6. Detection of Ostecalcin in gingival Crevicular fluid in a Group of Orthodontic Patients.Journal of International Society of Preventive & Community Dentistry
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ebru Olgun ErdemirDepartment of Periodontology, Faculty of Dentistry, Kirikkale University, Merkez, Kirikkale, Turkiye.
Meltem Karsiyaka HendekDepartment of Periodontology, Faculty of Dentistry, Kirikkale University, Merkez, Kirikkale, Turkiye.
H Gencay KeceliDepartment of Periodontology, Faculty of Dentistry, Hacettepe University, Sıhhiye, Ankara, Turkiye.
Teoman Z ApanDepartment of Medical Microbiology, Faculty of Medicine, Kirikkale University, Merkez, Kirikkale, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study is to evaluate the influence of regenerative periodontal therapy on clinical parameters and interleukin-8 (IL-8), IL-17 and soluble intercellular adhesion molecule-1 (sICAM-1) levels in gingival crevicular fluid (GCF) of subjects with chronic periodontitis (CP). MATERIALS AND

methodsFifteen patients received demineralized freeze-dried bone allograft (DFDBA) surgically to the site of infrabony defect. Clinical periodontal indices were recorded, and GCF samples were collected at baseline and at the 6(th) and the 9(th) month after the surgery.

resultsExcept plaque index, all clinical parameters improved following surgery (P < 0.05). The volume of GCF diminished from baseline to follow-up periods (P < 0.05). However, no effect was observed on the total amount of IL-8, IL-17 and sICAM-1 in GCF.

conclusionDFDBA improved clinical outcome in CP subjects and was effective on decreasing the volume of GCF, but no effect was determined on IL-8, IL-17 and sICAM-1. Findings did not indicate a direct relationship between biochemical parameters and periodontal healing after demineralized freeze-dried bone grafting.

Indexed as

Demineralized freeze-dried bone allograftgingival crevicular fluidinterleukin-17interleukin-8soluble intercellular adhesion molecule-1

Identifiers

PMID25713486
PMCPMC4319302

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.