SynthesisEnvironmental health perspectives2015
Natural-cause mortality and long-term exposure to particle components: an analysis of 19 European cohorts within the multi-center ESCAPE project.
Synthesis in Environmental health perspectives, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Environmental and Occupational Short-Term Exposure to Airborne Particles and FEVInternational journal of environmental research and public health · 2021Pooled it
- Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PMResearch report (Health Effects Institute) · 2021Pooled it
- Acute cardiovascular effects of controlled exposure to dilute Petrodiesel and biodiesel exhaust in healthy volunteers: a crossover study.Particle and fibre toxicology · 2021Trial
- Environmental Health Is Overlooked in Longevity Research.Antioxidants (Basel, Switzerland) · 2025Review
- Does Nonsteroidal Anti-inflammatory Drug Use Modify All-Cause and Cause-Specific Mortality Associated with PMEnvironment & health (Washington, D.C.) · 2025Article
- Long-term exposure to air pollution on cardio-respiratory, and lung cancer mortality: a systematic review and meta-analysis.Journal of environmental health science & engineering · 2024Review
- Application of artificial intelligence in quantifying lung deposition dose of black carbon in people with exposure to ambient combustion particles.Journal of exposure science & environmental epidemiology · 2024Article
- Primary Sulfate Is the Dominant Source of Particulate Sulfate during Winter in Fairbanks, Alaska.ACS ES&T air · 2024Article
- The biological interplay between air pollutants and miRNAs regulation in cancer.Frontiers in cell and developmental biology · 2024Review
- External exposome and all-cause mortality in European cohorts: the EXPANSE project.Frontiers in epidemiology · 2024Article
- California's zero-emission vehicle adoption brings air quality benefits yet equity gaps persist.Nature communications · 2023Article
- A Long Way from Steubenville: Environmental Epidemiology in a Rapidly Changing World.American journal of epidemiology · 2023Article
- Associations of Autism Spectrum Disorder with PMEnvironmental science & technology · 2023Article
- Disentangling associations between multiple environmental exposures and all-cause mortality: an analysis of European administrative and traditional cohorts.Frontiers in epidemiology · 2023Article
- Cigarette smoking and air pollution exposure and their effects on cardiovascular diseases.Frontiers in public health · 2023Review
- Associations between long-term exposures to airborne PMEnvironmental health : a global access science source · 2022Article
- Long-Term Exposure to Source-Specific Fine Particles and Mortality─A Pooled Analysis of 14 European Cohorts within the ELAPSE Project.Environmental science & technology · 2022Article
- Recent Insights into Particulate Matter (PMInternational journal of environmental research and public health · 2022Review
- Impacts of Built Environment on Risk of Women's Lung Cancer: A Case Study of China.International journal of environmental research and public health · 2022Article
- Long-term exposure to ambient air pollution and bladder cancer incidence in a pooled European cohort: the ELAPSE project.British journal of cancer · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
72 authors.
Funding
Abstract
backgroundStudies have shown associations between mortality and long-term exposure to particulate matter air pollution. Few cohort studies have estimated the effects of the elemental composition of particulate matter on mortality.
objectivesOur aim was to study the association between natural-cause mortality and long-term exposure to elemental components of particulate matter.
methodsMortality and confounder data from 19 European cohort studies were used. Residential exposure to eight a priori-selected components of particulate matter (PM) was characterized following a strictly standardized protocol. Annual average concentrations of copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc within PM size fractions ≤ 2.5 μm (PM2.5) and ≤ 10 μm (PM10) were estimated using land-use regression models. Cohort-specific statistical analyses of the associations between mortality and air pollution were conducted using Cox proportional hazards models using a common protocol followed by meta-analysis.
resultsThe total study population consisted of 291,816 participants, of whom 25,466 died from a natural cause during follow-up (average time of follow-up, 14.3 years). Hazard ratios were positive for almost all elements and statistically significant for PM2.5 sulfur (1.14; 95% CI: 1.06, 1.23 per 200 ng/m3). In a two-pollutant model, the association with PM2.5 sulfur was robust to adjustment for PM2.5 mass, whereas the association with PM2.5 mass was reduced.
conclusionsLong-term exposure to PM2.5 sulfur was associated with natural-cause mortality. This association was robust to adjustment for other pollutants and PM2.5.
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