Evidence map›Paper›PMID 25712186›Full record

ArticlePharmacogenomics2015

Pharmacogenomics in diverse practice settings: implementation beyond major metropolitan areas.

Elizabeth H Dorfman, Susan Brown Trinidad, Chelsea T Morales, Kevin Howlett, Wylie Burke, Erica L Woodahl

Abstract read
In one paragraph

Article in Pharmacogenomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  17. Democratizing Precision Medicine Through Community Engagement.Clinical pharmacology and therapeutics · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elizabeth H DorfmanInstitute for Public Health Genetics, University of Washington, Seattle, WA, USA.
Susan Brown Trinidad
Chelsea T Morales
Kevin Howlett
Wylie Burke
Erica L Woodahl

Funding

Surveillance genome sequencing to detect SARS-CoV-2 virus variants in MontanaP20GM103546 · NIGMS · UNIVERSITY OF MONTANA · PI BOWLER, BRUCE E · 2012 to 2021
$19.2M
Pharmacogenetics in Rural and Underserved PopulationsU01GM092676 · NIGMS · UNIVERSITY OF WASHINGTON · PI BURKE, WYLIE G., THUMMEL, KENNETH E. · 2010 to 2014
$9.9M
NIGMS NIH HHS P20 GM103546NIGMS NIH HHS U01 GM092676NIGMS NIH HHS U01GM092676
6 · The paper itself

Abstract

aimThe limited formal study of the clinical feasibility of implementing pharmacogenomic tests has thus far focused on providers at large medical centers in urban areas. Our research focuses on small metropolitan, rural and tribal practice settings. MATERIALS &

methodsWe interviewed 17 healthcare providers in western Montana regarding pharmacogenomic testing.

resultsParticipants were optimistic about the potential of pharmacogenomic tests, but noted unique barriers in small and rural settings including cost, adherence, patient acceptability and testing timeframe. Participants in tribal settings identified heightened sensitivity to genetics and need for community leadership approval as additional considerations.

conclusionImplementation differences in small metropolitan, rural and tribal communities may affect pharmacogenomic test adoption and utilization, potentially impacting many patients. Original submitted 3 September 2014; Revision submitted 3 December 2014.

Indexed as

AdultFemaleHealth Services, IndigenousHumansIndians, North AmericanMaleMiddle AgedMontanaPharmacogeneticsPractice Patterns, Physicians'Precision MedicineRural Health ServicesAlaska NativeAmerican Indianimplementationindigenous populationspharmacogeneticspharmacogenomicsrural

Identifiers

PMID25712186
PMCPMC4360986

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.