ArticleAutism research : official journal of the International Society for Autism Research2015
Replication of Standardized ADOS Domain Scores in the Simons Simplex Collection.
Article in Autism research : official journal of the International Society for Autism Research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Autism spectrum disorder profiles in RASopathies: A systematic review.Molecular genetics & genomic medicine · 2024Pooled it
- Meta-Analysis of the RDoC Social Processing Domain across Units of Analysis in Children and Adolescents.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Pooled it
- Arachidonic acid-derived dihydroxy fatty acids in neonatal cord blood relate symptoms of autism spectrum disorders and social adaptive functioning: Hamamatsu Birth Cohort for Mothers and Children (HBC Study).Psychiatry and clinical neurosciences · 2024Article
- Using the Griffiths Mental Development Scales to Evaluate a Developmental Profile of Children with Autism Spectrum Disorder and Their Symptomatologic Severity.Child psychiatry and human development · 2024Article
- Replication study for ADOS-2 cut-offs to assist evaluation of autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2022Article
- Eczema and related atopic diseases are associated with increased symptom severity in children with autism spectrum disorder.Translational psychiatry · 2022Article
- Article
- Analysis of Race and Sex Bias in the Autism Diagnostic Observation Schedule (ADOS-2).JAMA network open · 2022Article
- Delineating the autistic phenotype in children with neurofibromatosis type 1.Molecular autism · 2022Article
- Individual and Environmental Factors Affecting Adaptive Behavior of Toddlers with Autism Spectrum Disorder: Role of Parents' Socio-cultural Level.Journal of autism and developmental disorders · 2021Article
- Trajectories of Autism Symptom Severity Change During Early Childhood.Journal of autism and developmental disorders · 2021Article
- Selective Extraction of Cannabinoid Compounds from Cannabis Seed Using Pressurized Hot Water Extraction.Molecules (Basel, Switzerland) · 2020Article
- Autism Spectrum Disorder Symptom Profile Across the RASopathies.Frontiers in psychiatry · 2020Article
- Thermal Perceptual Thresholds are typical in Autism Spectrum Disorder but Strongly Related to Intra-individual Response Variability.Scientific reports · 2019Article
- Predictors of Inpatient Psychiatric Hospitalization for Children and Adolescents with Autism Spectrum Disorder.Journal of autism and developmental disorders · 2018Article
- FADS1-FADS2 and ELOVL2 gene polymorphisms in susceptibility to autism spectrum disorders in Chinese children.BMC psychiatry · 2018Article
- Severe abdominal pain and diarrhea - unusual multiple myeloma presentation with a severe prognosis: a case report.Journal of medical case reports · 2018Article
- Motor Skills as Moderators of Core Symptoms in Autism Spectrum Disorders: Preliminary Data From an Exploratory Analysis With Artificial Neural Networks.Frontiers in psychology · 2018Article
- The EU-AIMS Longitudinal European Autism Project (LEAP): clinical characterisation.Molecular autism · 2017Observational
- Multidimensional Influences on Autism Symptom Measures: Implications for Use in Etiological Research.Journal of the American Academy of Child and Adolescent Psychiatry · 2016Article
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2 authors.
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Abstract
Raw totals from diagnostic and screening measures for autism spectrum disorder (ASD) are frequently used as dimensional measures of autism symptom severity without appropriate correction for confounding factors, such as developmental level or non-ASD-specific behavior problems. Although these associated features are important to consider when diagnosing ASD and developing intervention plans, both researchers and clinicians sometimes need metrics of ASD severity that are not influenced by these factors. The Autism Diagnostic Observation Schedule (ADOS) domain calibrated severity scores (CSS) were created to provide separate estimates of social affect (SA-CSS) and restricted, repetitive behaviors (RRB-CSS) that are relatively independent of child characteristics (Hus et al., 2014). Using a sample of 2,509 probands with ASD from the Simons Simplex Collection (SSC), this study provides the first replication of the ADOS domain CSS in an independent sample. Consistent with the original standardization study, when applied to existing SSC data, the ADOS domain CSS were less influenced by age and cognitive ability compared to raw domain totals. Domain CSS were also relatively independent of behavior problems. Use of the ADOS domain CSS to assess relationships between ASD symptoms and genetic risk factors will increase confidence that associations reflect domain-specific relationships. Scores also offer less developmentally-influenced estimates of ASD severity for future phenotypic explorations in the SSC. This independent replication provides support for the application of the ADOS domain CSS in other samples, though further replication in population-based samples will be an important next step.
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