ArticleThe American journal of tropical medicine and hygiene2015
Performance of an HRP-2 rapid diagnostic test in Nigerian children less than 5 years of age.
Article in The American journal of tropical medicine and hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- High value of rapid diagnostic tests to diagnose malaria within children: A systematic review and meta-analysis.Journal of global health · 2020Pooled it
- Malaria Rapid Diagnostic Tests and Malaria Microscopy for Guiding Malaria Treatment of Uncomplicated Fevers in Nigeria and Prereferral Cases in 3 African Countries.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016Trial
- Effect of malaria training on community healthcare providers' compliance with malaria treatment guidelines in Nigeria using propensity score matching.Malaria journal · 2026Article
- Role of surveillance data in detecting malaria outbreaks in an epidemic-prone region in Kenya: findings from an investigation of a suspected outbreak in Nandi County.Malaria journal · 2024Article
- Article
- Experience and confidence in health technologies: evidence from malaria testing and treatment in Western Kenya.BMC public health · 2022Article
- PERSISTENCE OF PLASMODIUMAnnals of Ibadan postgraduate medicine · 2021Article
- Pharyngeal Carriage of Beta-HaemolyticTropical medicine and infectious disease · 2020Article
- Adherence to malaria rapid diagnostic test result among healthcare workers in Sokoto metropolis, Nigeria.Malaria journal · 2020Article
- Asymptomatic malaria infections and Pfmdr1 mutations in an endemic area of Nigeria.Malaria journal · 2019Article
- Article
- Trend of malaria cases in Kaduna State using routine surveillance data, 2011-2015.The Pan African medical journal · 2019Article
- Evaluation of the Clinical Proficiency of RDTs, Microscopy and Nested PCR in the Diagnosis of Symptomatic Malaria in Ilorin, North-Central, Nigeria.Open access Macedonian journal of medical sciences · 2018Article
- Practice of antimalarial prescription to patients with negative rapid test results and associated factors among health workers in Oyo State, Nigeria.The Pan African medical journal · 2018Article
- Performance of malaria rapid diagnostic test in febrile under-five children at Oni Memorial Children's Hospital in Ibadan, Nigeria, 2016.The Pan African medical journal · 2018Article
- Human Genetic Markers and Structural Prediction ofJournal of environmental and public health · 2018Article
- Demand-related factors influencing caregivers' awareness of malaria tests and health workers' testing practices, in Makarfi, Nigeria.Malaria journal · 2017Article
- Compliance With Malaria Rapid Diagnostic Testing by Community Health Workers in 3 Malaria-Endemic Countries of Sub-Saharan Africa: An Observational Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016Observational
- A malariometric survey of under-fives residing in indoor residual spraying-implementing and non-implementing communities of Lagos, Nigeria.Malaria journal · 2016Article
- Is Nigeria winning the battle against malaria? Prevalence, risk factors and KAP assessment among Hausa communities in Kano State.Malaria journal · 2016Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnostic performance of histidine-rich protein 2 (HRP-2)-based malaria rapid diagnostic test (RDT) was evaluated in a mesoendemic area for malaria, Kaduna, Nigeria. We compared RDT results with expert microscopy results of blood samples from 295 febrile children under 5 years. Overall, 11.9% (35/295) tested positive with RDT compared with 10.5% (31/295) by microscopy: sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 100%, 98.5%, 88.6%, and 100%, respectively. The RDT sensitivity was not affected by transmission season, parasite density, and age. Specificity and positive PV decreased slightly during the high-transmission season (97.5% and 83.3%). The RDT test positivity rates in the low- and high-transmission seasons were 9.4% and 13.5%, respectively. Overall, the test performance of this RDT was satisfactory. The findings of a low proportion of RDT false positives, no invalid and no false-negative results should validate the performance of RDTs in this context.
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