ArticleChembiochem : a European journal of chemical biology2015
A Photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase.
Article in Chembiochem : a European journal of chemical biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- ExploringMolecules (Basel, Switzerland) · 2024Review
- Review
- Virulent secondary metabolites of entomopathogenic bacteria genera, Xenorhabdus and Photorhabdus, inhibit phospholipase ABMC microbiology · 2020Article
- Article
- Variations of Indole Metabolites and NRPS-PKS Loci in Two Different Virulent Strains ofFrontiers in microbiology · 2020Article
- Bacteria of the GenusFrontiers in microbiology · 2018Review
- Secondary Metabolites Produced byJournal of nematology · 2017Article
- Light Sheet-based Fluorescence Microscopy of Living or Fixed and Stained Tribolium castaneum Embryos.Journal of visualized experiments : JoVE · 2017Article
- Stilbene epoxidation and detoxification in aThe Journal of biological chemistry · 2017Article
- Screening of the Antimicrobial Activity against Drug Resistant Bacteria ofFrontiers in microbiology · 2017Article
- LuxS-dependent AI-2 production is not involved in global regulation of natural product biosynthesis inPeerJ · 2017Article
- The Global Regulators Lrp, LeuO, and HexA Control Secondary Metabolism in Entomopathogenic Bacteria.Frontiers in microbiology · 2017Article
- Heterogeneous regulation of bacterial natural product biosynthesis via a novel transcription factor.Heliyon · 2016Article
- Live imaging of Tribolium castaneum embryonic development using light-sheet-based fluorescence microscopy.Nature protocols · 2015Article
Corrections and comments
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Authors and funding
24 authors at 11 institutions in 6 countries.
Funding
Abstract
Simple urea compounds ("phurealipids") have been identified from the entomopathogenic bacterium Photorhabdus luminescens, and their biosynthesis was elucidated. Very similar analogues of these compounds have been previously developed as inhibitors of juvenile hormone epoxide hydrolase (JHEH), a key enzyme in insect development and growth. Phurealipids also inhibit JHEH, and therefore phurealipids might contribute to bacterial virulence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.