Evidence map›Paper›PMID 25711415›Full record

ArticleDepression and anxiety2015

SUICIDAL THOUGHTS AND BEHAVIORS IN CHILDREN AND ADOLESCENTS WITH CHRONIC TIC DISORDERS.

Eric A Storch, Camille E Hanks, Jonathan W Mink, Joseph F McGuire, Heather R Adams, Erika F Augustine, Amy Vierhile, Alyssa Thatcher, Rebecca Bitsko, Adam B Lewin and 1 more

Abstract read
In one paragraph

Article in Depression and anxiety, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Reframing stigma in Tourette syndrome: an updated scoping review.European child & adolescent psychiatry · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Is Persistent Motor or Vocal Tic Disorder a Milder Form of Tourette Syndrome?Movement disorders : official journal of the Movement Disorder Society · 2021
    Article
  11. A Comprehensive Review of Tic Disorders in Children.Journal of clinical medicine · 2021
    Review
  12. Advances in the Treatment of Tourette's Disorder.Current psychiatry reports · 2019
    Review
  13. Article
  14. Article
  15. Suicidal ideation in youth with tic disorders.Journal of affective disorders · 2016
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eric A StorchRothman Center for Neuropsychiatry, Department of Pediatrics, University of South Florida, St. Petersburg, Florida.
Camille E HanksRothman Center for Neuropsychiatry, Department of Pediatrics, University of South Florida, St. Petersburg, Florida.
Jonathan W MinkDepartment of Neurology, University of Rochester, Rochester, New York.
Joseph F McGuireRothman Center for Neuropsychiatry, Department of Pediatrics, University of South Florida, St. Petersburg, Florida.
Heather R AdamsDepartment of Neurology, University of Rochester, Rochester, New York.
Erika F AugustineDepartment of Neurology, University of Rochester, Rochester, New York.
Amy VierhileDepartment of Neurology, University of Rochester, Rochester, New York.
Alyssa ThatcherDepartment of Neurology, University of Rochester, Rochester, New York.
Rebecca BitskoDivision of Human Development and Disability, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia.
Adam B LewinRothman Center for Neuropsychiatry, Department of Pediatrics, University of South Florida, St. Petersburg, Florida.
Tanya K MurphyRothman Center for Neuropsychiatry, Department of Pediatrics, University of South Florida, St. Petersburg, Florida.

Funding

University of Rochester Child Neurology Academic Development ProgramK12NS066098 · NINDS · UNIVERSITY OF ROCHESTER · PI MINK, JONATHAN W. · 2009 to 2013
$1.1M
Quality of life, Comorbidities, and Health Service Utilization in Youth with TicU01DD000509 · DD · UNIVERSITY OF SOUTH FLORIDA · PI MURPHY, MD, TANYA K · 2009 to 2011
$475k
Intramural CDC HHS CC999999NCBDD CDC HHS U01 DD000509NCBDD CDC HHS U01DD000509-01NINDS NIH HHS K12 NS066098
6 · The paper itself

Abstract

objectiveDespite evidence of elevated risk factors for suicidal thoughts and behavior in youth with Tourette syndrome and chronic tic disorders (CTD), few studies have actually examined that relationship. This study documented the frequency and clinical correlates of suicidal thoughts and behaviors in a sample of children and adolescents with CTD (N = 196, range 6-18 years old). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Centers for Disease Control.

methodYouth and parents completed a battery of measures that assessed co-occurring psychiatric diagnoses, child emotional and behavioral symptoms, and impairment due to tics or co-occurring conditions.

resultsA structured diagnostic interview identified that 19 youths with CTD (9.7%) experienced suicidal thoughts and/or behaviors, which was elevated compared to 3 youths (3%) who experienced these thoughts in a community control sample (N = 100, range 6-18 years old, P = .03). For youth with CTD, suicidal thoughts and behaviors were frequently endorsed in the context of anger and frustration. The Child Behavior Checklist (CBCL) anxious/depressed, withdrawn, social problems, thought problems, and aggressive behavior subscales, as well as the total internalizing problems scale, were associated with the presence of suicidal thoughts and/or behaviors. Suicidal thoughts and/or behaviors were significantly associated with tic symptom severity; tic-related impairment; and obsessive-compulsive, depressive, anxiety, and attention-deficit/hyperactivity disorders' symptom severity. CBCL anxiety/depression scores mediated the relationship between tic severity and suicidal thoughts and behaviors.

conclusionsFindings suggest that about 1 in 10 youth with CTD experience suicidal thoughts and/or behaviors, which are associated with a more complex clinical presentation and often occur in the presence of anger and frustration.

Indexed as

Suicidal IdeationAdolescentAnxietyAnxiety DisordersAttention Deficit Disorder with HyperactivityChildDepressionFemaleHumansMaleSeverity of Illness IndexTic DisordersTourette Syndromeassessmentchildrensuicidal ideationsuicidetic disorderticsTourette syndrome

Identifiers

PMID25711415
PMCPMC4547888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.