Evidence map›Paper›PMID 25710528›Full record

ReviewDevelopmental cell2015

Evolution of patterning systems and circuit elements for locomotion.

Heekyung Jung, Jeremy S Dasen

Open access · bronzeAbstract readReview
In one paragraph

Review in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. V2b Neurons Act via Multiple Targets to Produce in Phase Inhibition during Locomotion.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  8. Molecular and Cellular Mechanisms of Motor Circuit Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Hox Proteins in the Regulation of Muscle Development.Frontiers in cell and developmental biology · 2021
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Heekyung JungHoward Hughes Medical Institute (HHMI), NYU Neuroscience Institute, Department of Neuroscience and Physiology, New York University School of Medicine, New York, NY 10016, USA.
Jeremy S DasenHoward Hughes Medical Institute (HHMI), NYU Neuroscience Institute, Department of Neuroscience and Physiology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: jeremy.dasen@nyumc.org.
Howard Hughes Medical Institute · USNew York University · US

Funding

Transcriptional Control of Motor Neuron Identity and Connectivity. - Renewal - 1R01NS062822 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DASEN, JEREMY S · 2009 to 2019
$3.9M
Howard Hughes Medical InstituteNINDS NIH HHS R01 NS062822
6 · The paper itself

Abstract

Evolutionary modifications in nervous systems enabled organisms to adapt to their specific environments and underlie the remarkable diversity of behaviors expressed by animals. Resolving the pathways that shaped and modified neural circuits during evolution remains a significant challenge. Comparative studies have revealed a surprising conservation in the intrinsic signaling systems involved in early patterning of bilaterian nervous systems but also raise the question of how neural circuit compositions and architectures evolved within specific animal lineages. In this review, we discuss the mechanisms that contributed to the emergence and diversity of animal nervous systems, focusing on the circuits governing vertebrate locomotion.

Indexed as

Biological EvolutionAnimalsBody PatterningHumansLocomotionNervous SystemSignal TransductionVertebrates

Identifiers

PMID25710528
PMCPMC4339819
OpenAlexW2160513150

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.