Evidence map›Paper›PMID 25710527›Full record

ReviewDevelopmental cell2015

The evolution of early neurogenesis.

Volker Hartenstein, Angelika Stollewerk

Abstract readReview
In one paragraph

Review in Developmental cell, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Early nervous system development in the chaetognathFrontiers in cell and developmental biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. AMAZING PAPERS in NEUROSCIENCE: Teaching Neurodevelopment Through the Discovery of Adult Neurogenesis.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2025
    Review
  11. Experimental Neurogenesis in the Embryos of the Gecko Paroedura picta.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  12. Article
  13. A wound-induced differentiation trajectory for neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Parallel Evolution of Transcription Factors in Basal Metazoans.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Volker HartensteinDepartment of Molecular Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: volkerh@mcdb.ucla.edu.
Angelika StollewerkSchool of Biological and Chemical Sciences, Queen Mary University of London, Mile End Road, London E1 4NS, UK. Electronic address: a.stollewerk@qmul.ac.uk.

Funding

Lineage-associated wiring properties of Drosphila brain neuronsR01NS054814 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HARTENSTEIN, VOLKER, LOUIS, MATTHIEU R. P. J. C. G. · 2006 to 2025
$6.6M
Biotechnology and Biological Sciences Research Council BB/F021909/1NINDS NIH HHS R01 NS054814
6 · The paper itself

Abstract

The foundation of the diverse metazoan nervous systems is laid by embryonic patterning mechanisms, involving the generation and movement of neural progenitors and their progeny. Here we divide early neurogenesis into discrete elements, including origin, pattern, proliferation, and movement of neuronal progenitors, which are controlled by conserved gene cassettes. We review these neurogenetic mechanisms in representatives of the different metazoan clades, with the goal to build a conceptual framework in which one can ask specific questions, such as which of these mechanisms potentially formed part of the developmental "toolkit" of the bilaterian ancestor and which evolved later.

Indexed as

Biological EvolutionAnimalsGene Expression Regulation, DevelopmentalHumansNervous SystemNervous System Physiological PhenomenaNeurogenesis

Identifiers

PMID25710527
PMCPMC5987553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.