ReviewJournal of alternative and complementary medicine (New York, N.Y.)2015
Manual and electrical needle stimulation in acupuncture research: pitfalls and challenges of heterogeneity.
Review in Journal of alternative and complementary medicine (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 62 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Electroacupuncture Frequency-related Effects on Chronic Low Back Pain in Older Adults: Triple-blind, 12-month Protocol for a Randomized Controlled Trial.
Evaluation of Integrated Optimization Schemes for Female Stress Incontinence
Who cites it
62 citing papers in PubMed, 9 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- The interventional effect of acupuncture on overall cognitive function in Alzheimer's disease spectrum disorders: A meta-analysis.Journal of Alzheimer's disease : JAD · 2026Pooled it
- Effects of acupuncture on mild cognitive impairment via the microbiota-gut-brain axis: a systematic review.Frontiers in neuroscience · 2026Pooled it
- Clinical effect and contributing factors of acupuncture for knee osteoarthritis: a systematic review and pairwise and exploratory network meta-analysis.BMJ evidence-based medicine · 2024Pooled it
- Risk of Hepatitis C Virus Transmission through Acupuncture: A Systematic Review and Meta-Analysis.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023Pooled it
- Global Trend in the Research and Development of Acupuncture Treatment on Parkinson's Disease From 2000 to 2021: A Bibliometric Analysis.Frontiers in neurology · 2022Pooled it
- Electroacupuncture for the treatment of frozen shoulder: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Acupuncture for depression.The Cochrane database of systematic reviews · 2018Pooled it
- Pooled it
- The quality of reporting of randomized controlled trials of electroacupuncture for stroke.BMC complementary and alternative medicine · 2016Pooled it
- Percutaneous tendon dry needling and thrust manipulation as an adjunct to multimodal physical therapy in patients with lateral elbow tendinopathy: A multicenter randomized clinical trial.Clinical rehabilitation · 2024Trial
- Efficacy of short duration versus conventional electroacupuncture in the treatment of obesity: a randomized crossover study.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2022Trial
- Efficacy of electro-acupuncture in postpartum with diastasis recti abdominis: A randomized controlled clinical trial.Frontiers in public health · 2022Trial
- Effect of Electroacupuncture vs Sham Treatment on Change in Pain Severity Among Adults With Chronic Low Back Pain: A Randomized Clinical Trial.JAMA network open · 2020Trial
- Periosteal Electrical Dry Needling as an Adjunct to Exercise and Manual Therapy for Knee Osteoarthritis: A Multicenter Randomized Clinical Trial.The Clinical journal of pain · 2018Trial
- Trial
- Rewiring the primary somatosensory cortex in carpal tunnel syndrome with acupuncture.Brain : a journal of neurology · 2017Trial
- Moxibustion for pain relief in patients with primary dysmenorrhea: A randomized controlled trial.PloS one · 2017Trial
- Trial
- Electroacupuncture and splinting versus splinting alone to treat carpal tunnel syndrome: a randomized controlled trial.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2016Trial
- Feasibility and Preliminary Effects of Adding Percutaneous Electrical Nerve Stimulation to a Pain Education and Exercise Program in Patients with Knee Osteoarthritis: A Pilot Randomized Controlled Trial.Journal of clinical medicine · 2026Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 10 institutions in 4 countries.
Funding
Abstract
In the field of acupuncture research there is an implicit yet unexplored assumption that the evidence on manual and electrical stimulation techniques, derived from basic science studies, clinical trials, systematic reviews, and meta-analyses, is generally interchangeable. Such interchangeability would justify a bidirectional approach to acupuncture research, where basic science studies and clinical trials each inform the other. This article examines the validity of this fundamental assumption by critically reviewing the literature and comparing manual to electrical acupuncture in basic science studies, clinical trials, and meta-analyses. The evidence from this study does not support the assumption that these techniques are interchangeable. This article also identifies endemic methodologic limitations that have impaired progress in the field. For example, basic science studies have not matched the frequency and duration of manual needle stimulation to the frequency and duration of electrical stimulation. Further, most clinical trials purporting to compare the two types of stimulation have instead tested electroacupuncture as an adjunct to manual acupuncture. The current findings reveal fundamental gaps in the understanding of the mechanisms and relative effectiveness of manual versus electrical acupuncture. Finally, future research directions are suggested to better differentiate electrical from manual simulation, and implications for clinical practice are discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.