Evidence map›Paper›PMID 25709916›Full record

ArticleInternational journal of ophthalmology2015

Comparison of retinal nerve fiber layer and macular thickness measurements with Stratus OCT and OPKO/OTI OCT devices in healthy subjects.

Ahmet Ozkok, Julide Canan Umurhan Akkan, Nevbahar Tamcelik, Mehmet Erdogan, Didar Ucar Comlekoglu, Rengin Yildirim

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Article in International journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ahmet OzkokDepartment of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey.
Julide Canan Umurhan AkkanDepartment of Ophthalmology, School of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
Nevbahar TamcelikDepartment of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey.
Mehmet ErdoganDepartment of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey.
Didar Ucar ComlekogluDepartment of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey.
Rengin YildirimDepartment of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University, Istanbul 34098, Turkey.
Istanbul University-Cerrahpaşa · TRBezmiâlem Vakıf Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare retinal nerve fiber layer (RNFL) and macular thickness measurements obtained with the Stratus optical coherence tomography (OCT) and OPKO/OTI OCT devices.

methodsIncluded in the study were 59 eyes of 30 participants. All measurements for each eye were done on the same day with both devices. Student's paired t-tests were used to compare the central macular thickness and RNFL measurements of the Stratus OCT and OPKO/OTI OCT. Pearson correlation was used to assess the relationship between the devices. Coefficient of variation (COV) was calculated to assess intersession repeatability.

resultsUsing both the Stratus OCT and OPKO/OTI OCT, respectively, the measured mean average RNFL thicknesses were 98.9±11.1 µm and 115.1±9.6 µm (P=0.001), and the measured mean central retinal thicknesses (CRT) were 196.2±18.8 µm and 204.5±21.1 µm (P<0.001). Measured by the two devices, the RNFL thickness values were correlated in all quadrants, as were the retinal thickness values except the inferior outer sector. COV for average RNFL and CRT thickness were 2.9% and 4.6% for Stratus OCT, and 2.1% and 4.2% for OPKO/OTI OCT, respectively.

conclusionWe found good reproducibility of RNFL and retina thickness measurements for both Stratus OCT and OPKO/OTI OCT devices. However, even though the two OCT systems provided statistically correlated results, the values for both RNFL and macular thickness were statistically different. RNFL and macular thickness measurements with the OPKO/OTI OCT were higher than that of the Stratus OCT; therefore, the two OCT systems cannot be used interchangeably for the measurements of RNFL and macular thickness.

Indexed as

macular thicknessOPKO/OTI OCToptical coherence tomographyretinal nerve fiber layerStratus optical coherence tomography

Identifiers

PMID25709916
PMCPMC4325250
OpenAlexW49945303

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.