ArticleInternational journal of spine surgery2015
Prospective analysis of a new bone graft in lumbar interbody fusion: results of a 2- year prospective clinical and radiological study.
Article in International journal of spine surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05038527 (ABM/P-15 Bone Graft vs Traditional Bone Graft in Adult Spinal Deformity Surgery - a Randomized Controlled Clinical Trial), which is not on this map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ABM/P-15 Bone Graft vs Traditional Bone Graft in Adult Spinal Deformity Surgery - a Randomized Controlled Clinical Trial
Who cites it
22 citing papers in PubMed, 36 citations in OpenAlex.
- Trial
- Comparative analysis of autograftJournal of spine surgery (Hong Kong) · 2026Article
- Peptide-conjugated biodegradable polyester scaffolds for bone regeneration.Biomaterials · 2026Review
- Lumbar Plexopathy and Exploration Following an Oblique Lumbar Interbody Fusion (OLIF) iFactor-Associated Complication: A Case Report.Case reports in orthopedics · 2026Article
- Article
- Efficacy and Outcome Measurement of iFactor/ABM/P-15 in Lumbar Spine Surgery: A Systematic Review.Global spine journal · 2024Review
- Safety and Reoperation Rates in Non-instrumented Lumbar Fusion Surgery: Secondary Report From a Randomized Controlled Trial of ABM/P-15 vs Allograft With Minimum 5 years Follow-Up.Global spine journal · 2024Article
- Bone Grafting Options for Single-Level TLIF: So Many Options, What Is the Evidence?International journal of spine surgery · 2023Article
- Comparative Analysis of ABM/P-15, Bone Morphogenic Protein and Demineralized Bone Matrix after Instrumented Lumbar Interbody Fusion.Journal of Korean Neurosurgical Society · 2022Article
- Peptide Enhanced Bone Graft Substitute Presents Improved Short-Term Increase in Bone Volume and Construct Stiffness Compared to Iliac Crest Autologous Bone in an Ovine Lumbar Interbody Fusion Model.Global spine journal · 2022Article
- Does the use of i-FACTOR bone graft affect bone healing in those undergoing periacetabular osteotomy (PAO) for developmental dysplasia of the hip (DDH)? A retrospective study.Journal of hip preservation surgery · 2022Article
- The Impact of Osteobiologic Subtype Selection on Perioperative Complications and Hospital-Reported Charges in Single- and Multi-Level Lumbar Spinal Fusion.International journal of spine surgery · 2021Article
- Three- and 4-Level Lumbar Arthrodesis Using Adjunctive Pulsed Electromagnetic Field Stimulation: A Multicenter Retrospective Evaluation of Fusion Rates and a Review of the Literature.International journal of spine surgery · 2021Article
- Cost-Effectiveness of Peptide Enhanced Bone Graft i-Factor versus Use of Local Autologous Bone in Anterior Cervical Discectomy and Fusion Surgery.ClinicoEconomics and outcomes research : CEOR · 2021Article
- Arthroscopic Contribution of Synthetic Graft in Tibiotalocalcaneal Arthroscopic Fusions.Cureus · 2020Article
- Graft Materials and Biologics for Spinal Interbody Fusion.Biomedicines · 2019Review
- ISASS Recommendations and Coverage Criteria for Bone Graft Substitutes used in Spinal Surgery.International journal of spine surgery · 2018Article
- Bone regeneration strategies: Engineered scaffolds, bioactive molecules and stem cells current stage and future perspectives.Biomaterials · 2018Review
- Heterotopic ossification following use of i-Factor for spinal fusion in Mucopolysaccharidosis 1: a case report.Journal of surgical case reports · 2018Article
- Anterior cervical discectomy and fusion (ACDF) autograft versus graft substitutes: what do patients prefer?-A clinical study.Journal of spine surgery (Hong Kong) · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study examined the efficacy and safety of bone graft material ABM/P-15 (iFACTOR) for use in posterior lumbar interbody fusion. ABM/P-15 has been used safely for more than a decade in dental applications.
methodsForty patients underwent PLIF surgery, with each patient as control. Assessments up to 24 months included radiographs, CT scan, VAS, and ODI. Primary success criteria were fusion and safety.
resultsIntra-cage bridging bone occurred earlier with ABM/P-15 than autograft (97.73% vs. 59.09% at 6 months). On average pain decreased 29 points and function improved 43 points. Radio dense material outside the disk space occurred more frequently with ABM/P-15 than autograft, without clinical consequence.
conclusionsThis study suggests that ABM/P-15 has equal or greater efficacy at 6 and 12 months. Pain improvements exceeded success criteria at all time points. Functional improvement exceeded success criteria at all time points. CLINICAL RELEVANCE: This study explores the safety and efficacy of an osteobiologic peptide enhanced bone graft material as a viable alternative to autograft and its attendant risks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.