Evidence map›Paper›PMID 25709806›Full record

ArticleChemical science2015

Light-induced Crosslinkable Semiconducting Polymer Dots.

Yue Zhang, Fangmao Ye, Wei Sun, Jiangbo Yu, I-Che Wu, Yu Rong, Yong Zhang, Daniel T Chiu

Abstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. A dual-responsive nanocapsuleChemical science · 2016
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yue ZhangDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Fangmao YeDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Wei SunDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Jiangbo YuDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
I-Che WuDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Yu RongDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Yong ZhangDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.
Daniel T ChiuDepartment of Chemistry, University of Washington, Seattle, Washington 98195, United States.

Funding

High-Resolution Analysis of Synaptic ProteinsR01NS052637 · NINDS · UNIVERSITY OF WASHINGTON · PI CHIU, DANIEL T · 2005 to 2013
$3.2M
Ultra-Bright Probes with Ultra-Narrow Emission for Molecular and Cellular AnalysiR21CA186798 · NCI · UNIVERSITY OF WASHINGTON · PI CHIU, DANIEL T · 2014 to 2016
$672k
NCI NIH HHS R21 CA186798NINDS NIH HHS R01 NS052637
6 · The paper itself

Abstract

This paper describes a synthetic approach for photocrosslinkable polyfluorene (pc-PFO) semiconducting polymer dots, and demonstrates their superior ability to crosslink and form 3-D intermolecular polymer networks. The crosslinked pc-PFO Pdots are equipped with excellent encapsulating ability of functional small molecules. Optimum conditions of light irradiation on pc-PFO Pdots were investigated and clarified by using polymer thin films as a model. By employing the optimal light irradiation conditions, we successfully crosslinked pc-PFO Pdots and studied their particle sizes, photophysical, and colloidal properties. Single-particle imaging and dynamic-light-scattering measurements were conducted to understand the behaviors of photocrosslinked Pdots. Our results indicate pc-PFO Pdots can be easily photocrosslinked and the crosslinked species have excellent colloidal stability, physical and chemical stability, fluorescence brightness, and specific binding properties for cellular labeling. Considering that optical stimulus can work remotely, cleanly, and non-invasively, this study should pave the way for a promising approach to further develop stimuli-responsive ultrabright and versatile Pdot probes for biomedical imaging.

Identifiers

PMID25709806
PMCPMC4335711

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.