Evidence map›Paper›PMID 25709745›Full record

ReviewThe World Allergy Organization journal2014

Oral and sublingual immunotherapy for food allergy.

Uyenphuong H Le, A Wesley Burks

Open access · goldAbstract readReview
In one paragraph

Review in The World Allergy Organization journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Immunotherapy (oral and sublingual) for food allergy to fruits.The Cochrane database of systematic reviews · 2015
    Pooled it
  2. Regional Differences in Food Allergies.Clinical reviews in allergy & immunology · 2019
    Review
  3. Review
  4. Side effects and their impact on the success of milk oral immunotherapy (OIT) in children.International journal of immunopathology and pharmacology · 2017
    Article
  5. Feasibility of sustained response through long-term dosing in food allergy immunotherapy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2017
    Article
  6. A practical view of immunotherapy for food allergy.Korean journal of pediatrics · 2016
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Uyenphuong H LeDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill NC 260 MacNider Hall, CB 7220, Chapel Hill, NC 27599-7220 USA.
A Wesley BurksDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill NC 260 MacNider Hall, CB 7220, Chapel Hill, NC 27599-7220 USA.
University of North Carolina at Chapel Hill · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IgE-mediated food allergy is a potentially life-threatening allergic disease with an increase in prevalence in developed countries over the past 15 years. Currently, there are no approved forms of therapy and the standard of care is dietary restriction and ready access to emergency medications, such as self-injectable epinephrine and antihistamines. Allergen-specific modalities of treatment currently being studied include oral immunotherapy (OIT) and sublingual immunotherapy (SLIT). Both forms demonstrate the ability to desensitize patients to a variety of specific food allergens and show great promise. However, more research is needed to evaluate the safety and efficacy of OIT and SLIT prior to routine use in clinical practice.

Indexed as

DesensitizationFood allergyOral immunotherapySublingual immunotherapyTolerance

Identifiers

PMID25709745
PMCPMC4325942
OpenAlexW1971156666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.