ReviewJournal of pain research2015
Chronic pain management in the obese patient: a focused review of key challenges and potential exercise solutions.
Review in Journal of pain research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 5 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Effects of aquatic exercise on pain and physical function in overweight/obese patients with lower limb osteoarthritis: a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Associations between lifestyle-related risk factors and back pain: a systematic review and meta-analysis of Mendelian randomization studies.BMC musculoskeletal disorders · 2024Pooled it
- A Mixed Comparison of Interventions for Kinesiophobia in Individuals With Musculoskeletal Pain: Systematic Review and Network Meta-Analysis.Frontiers in psychology · 2022Pooled it
- Physical activity motives, barriers, and preferences in people with obesity: A systematic review.PloS one · 2021Pooled it
- The lived experiences of being physically active when morbidly obese: A qualitative systematic review.International journal of qualitative studies on health and well-being · 2015Pooled it
- Trial
- Effects of a High-Intensity Exercise Program on Weight Regain and Cardio-metabolic Profile after 3 Years of Bariatric Surgery: A Randomized Trial.Scientific reports · 2020Trial
- Effect of a low-intensity, self-management lifestyle intervention on knee pain in community-based young to middle-aged rural women: a cluster randomised controlled trial.Arthritis research & therapy · 2018Trial
- Does low and heavy load resistance training affect musculoskeletal pain in overweight and obese women? Secondary analysis of a randomized controlled trial.Brazilian journal of physical therapyTrial
- The mediating effect of 24-h movement behaviors in the association between obesity-related comorbidities and depression: evidence from a large-scale cohort study.European archives of psychiatry and clinical neuroscience · 2026Article
- Cardiorespiratory fitness and pain severity: Longitudinal associations from the general population-The HUNT study.Pain reports · 2026Article
- Exploring Sex Differences in Physical Activity Patterns Among Individuals with Schizophrenia Spectrum Disorders: Insights from the Diapason Project.Journal of clinical medicine · 2026Article
- Integrating patient-reported weight gain cause narratives into personalized obesity management: a data-driven approach with natural language processing and machine learning.Frontiers in nutrition · 2026Article
- Perceived benefits of treatment for obesity with retatrutide: A qualitative study of patients in a phase 2 clinical trial.Obesity pillars · 2025Article
- Pain characteristics and psychological factors that mediate the association between obesity and outcomes of interdisciplinary pain rehabilitation: a registry-based cohort study.Annals of medicine · 2025Article
- Time-restricted feeding modulates neuron-glial interactions and circadian rhythm in the spinal cord of male Wistar rats fed a high-fat diet.Spinal cord · 2025Article
- A risk factor prediction model for moderate-to-severe postoperative pain in patients undergoing laparoscopic sleeve gastrectomy.Medicine · 2025Article
- Effects of whole-body cryostimulation on spinal and shoulder range of motion in individuals with obesity.Frontiers in rehabilitation sciences · 2025Article
- Youths with Extreme Obesity: A High-Risk Group for Pain and Mental Health Impairments.Obesity facts · 2025Article
- A Missing Puzzle in Preclinical Studies-Are CCR2, CCR5, and Their Ligands' Roles Similar in Obesity-Induced Hypersensitivity and Diabetic Neuropathy?-Evidence from Rodent Models and Clinical Studies.International journal of molecular sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In obese persons, general and specific musculoskeletal pain is common. Emerging evidence suggests that obesity modulates pain via several mechanisms such as mechanical loading, inflammation, and psychological status. Pain in obesity contributes to deterioration of physical ability, health-related quality of life, and functional dependence. We present the accumulating evidence showing the interrelationships of mechanical stress, inflammation, and psychological characteristics on pain. While acute exercise may transiently exacerbate pain symptoms, regular participation in exercise can lower pain severity or prevalence. Aerobic exercise, resistance exercise, or multimodal exercise programs (combination of the two types) can reduce joint pain in young and older obese adults in the range of 14%-71.4% depending on the study design and intervention used. While published attrition rates with regular exercise are high (∼50%), adherence to exercise may be enhanced with modification to exercise including the accumulation of several exercise bouts rather than one long session, reducing joint range of motion, and replacing impact with nonimpact activity. This field would benefit from rigorous comparative efficacy studies of exercise intensity, frequency, and mode on specific and general musculoskeletal pain in young and older obese persons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.