Trial reportJournal of science and medicine in sport2016
Enhanced Exercise Therapy in Parkinson's disease: A comparative effectiveness trial.
Trial report in Journal of science and medicine in sport, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Exercise as a potent antidepressant intervention in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials.Frontiers in psychology · 2026Pooled it
- Physical Therapist Management of Parkinson Disease: A Clinical Practice Guideline From the American Physical Therapy Association.Physical therapy · 2022Guideline
- Occupational Therapy Interventions for Instrumental Activities of Daily Living for Adults With Parkinson's Disease: A Systematic Review.The American journal of occupational therapy : official publication of the American Occupational Therapy Association · 2021Pooled it
- Pooled it
- Trial
- Rehabilitation Strategies for Sleep and Autonomic Symptoms in Parkinson's Disease.Current neurology and neuroscience reports · 2025Review
- Intrarater Reliability and Agreement of Blood Pressure, Arterial Stiffness, and Heart Rate Variability Assessments in Patients With Parkinson's Disease.Arquivos brasileiros de cardiologia · 2024Article
- Adherence to Non-Pharmacological Interventions in Parkinson's Disease: A Rapid Evidence Assessment of the Literature.Journal of Parkinson's disease · 2024Review
- Perceptions of aquatic physiotherapy and health-related quality of life among people with Parkinson's disease.Health expectations : an international journal of public participation in health care and health policy · 2021Article
- Cardiopulmonary Function and Aerobic Exercise in Parkinson's: A Systematic Review of the Literature.Movement disorders clinical practice · 2020Review
- Non-Motor Symptoms after One Week of High Cadence Cycling in Parkinson's Disease.International journal of environmental research and public health · 2019Article
- Exercise as a Positive Modulator of Brain Function.Molecular neurobiology · 2018Review
- Peer Coaching Through mHealth Targeting Physical Activity in People With Parkinson Disease: Feasibility Study.JMIR mHealth and uHealth · 2018Article
- Exercise-induced increase in brain-derived neurotrophic factor in human Parkinson's disease: a systematic review and meta-analysis.Translational neurodegeneration · 2018Review
- A randomized trial of individual versus group-format exercise and self-management in individuals with Parkinson's disease and comorbid depression.Patient preference and adherence · 2017Article
- BrainCycles: Experimental Setup for the Combined Measurement of Cortical and Subcortical Activity in Parkinson's Disease Patients during Cycling.Frontiers in human neuroscience · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesExercise can improve motor function in people with Parkinson's disease but depression reduces the motivation to participate in regular exercise. The aim of this study was to develop a novel Enhanced Exercise Therapy program that uses manual-driven guided exercise and peer-facilitated psychoeducation for individuals with Parkinson's disease and depression.
design24 week randomized controlled design.
methodsThirty individuals were randomized to Enhanced Exercise Therapy or self-guided therapy, and evaluated at baseline, 12-weeks and at 24-weeks. Enhanced Exercise Therapy included group exercise and group psychoeducation for 12 weeks. Between 13 and 24 weeks, individuals had access to the fitness facility but group sessions were not held. Self-guided therapy included written guidelines for a self-paced exercise program and psychoeducation. Primary outcome measures included the number of exercise sessions and International Physical Activity Questionnaire score. Secondary measures included resting heart rate, supine blood pressure, estimated VO2max and incidence of orthostatic hypotension.
resultsTwenty four individuals completed the study (80% retention) and both groups attended similar number of exercise sessions. There were no significant changes in cardiovascular fitness measures but there was a significant increase in the amount of physical activity in the Enhanced Exercise Therapy group and a decrease in the self-guided therapy group during the post-intervention period.
conclusionsEnhanced Exercise Therapy appears to promote engagement in an exercise program and more physical activity, even after group sessions were concluded in individuals with Parkinson's disease and depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.