Evidence map›Paper›PMID 25708428›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2015

In-situ formation of growth-factor-loaded coacervate microparticle-embedded hydrogels for directing encapsulated stem cell fate.

Oju Jeon, David W Wolfson, Eben Alsberg

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Jammed Micro-Flake Hydrogel for Four-Dimensional Living Cell Bioprinting.Advanced materials (Deerfield Beach, Fla.) · 2022
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Oju JeonDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, 44106, USA.
David W Wolfson
Eben Alsberg

Funding

TRAINING PROGRAM IN MUSCULOSKELETAL RESEARCHT32AR007505 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI TRIOLO, RONALD J · 1986 to 2023
$6.3M
Driving Tissue Formation by Inductive Stem Cell Sheet TechnologyR01AR063194 · NIAMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALSBERG, EBEN · 2012 to 2016
$1.7M
Growth Plate RegenerationR21AR061265 · NIAMS · CLEVELAND CLINIC LERNER COM-CWRU · PI ALSBERG, EBEN, BALLOCK, ROBERT TRACY · 2012 to 2013
$392k
Controlled, Sustained Delivery of siRNA to hMSCs for Enhanced Bone RegenerationR56DE022376 · NIDCR · CASE WESTERN RESERVE UNIVERSITY · PI ALSBERG, EBEN · 2012 to 2012
$346k
NIAMS NIH HHS R01 AR063194NIAMS NIH HHS R01AR063194NIAMS NIH HHS R21 AR061265NIAMS NIH HHS R21AR061265NIAMS NIH HHS T32 AR007505NIAMS NIH HHS T32AR007505NIDCR NIH HHS R56 DE022376NIDCR NIH HHS R56DE022376
6 · The paper itself

Abstract

The spontaneous formation of coacervate microdroplet-laden photo-crosslinked hydrogels derived from the simple mixing of oxidized, methacrylated alginate (OMA) and methacrylated gelatin (GelMA) enables simultaneous creation of drug-laden microdroplets and encapsulation of stem cells in photopolymerized coacervate hydrogels under physiological conditions. This can be utilized as a novel platform for in situ formation of localized, sustained bioactive molecule delivery to encapsulate stem cells for therapeutic applications.

Indexed as

MicrospheresCapsulesHydrogelsStem CellsTissue EngineeringTissue ScaffoldsCapsulesHydrogelsalginatecoacervategelatinmicrodropletmicroencapsulation

Identifiers

PMID25708428
PMCPMC4408272

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.