Evidence map›Paper›PMID 25708095›Full record

ArticleBMC bioinformatics2015

Network tuned multiple rank aggregation and applications to gene ranking.

Wenhui Wang, Xianghong Zhou, Zhenqiu Liu, Fengzhu Sun

Abstract read
In one paragraph

Article in BMC bioinformatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wenhui Wang
Xianghong Zhou
Zhenqiu Liu
Fengzhu Sun

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Implications of haplotype structure in the human genomeP50HG002790 · NHGRI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TAVARE, SIMON · 2003 to 2013
$29.9M
MAPGen Knowledge Base (MAPGenKB) and Coordination CenterU01HL108634 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CRANDALL, EDWARD DAVID, ZHOU, XIANGHONG JASMINE · 2011 to 2015
$5.3M
The Phathophenotype Landscape of Complex DiseaseU01HL108630 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LOSCALZO, JOSEPH · 2011 to 2014
$2.7M
NCATS NIH HHS UL1 TR000124NHGRI NIH HHS P50HG002790NHLBI NIH HHS U01HL108630NHLBI NIH HHS U01 HL108634
6 · The paper itself

Abstract

With the development of various high throughput technologies and analysis methods, researchers can study different aspects of a biological phenomenon simultaneously or one aspect repeatedly with different experimental techniques and analysis methods. The output from each study is a rank list of components of interest. Aggregation of the rank lists of components, such as proteins, genes and single nucleotide variants (SNV), produced by these experiments has been proven to be helpful in both filtering the noise and bringing forth a more complete understanding of the biological problems. Current available rank aggregation methods do not consider the network information that has been observed to provide vital contributions in many data integration studies. We developed network tuned rank aggregation methods incorporating network information and demonstrated its superior performance over aggregation methods without network information.

Indexed as

Computational BiologyFungal ProteinsGene OntologyProtein Interaction MappingSoftwareFungal Proteins

Identifiers

PMID25708095
PMCPMC4331705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.