Evidence map›Paper›PMID 25706196›Full record

ReviewCurrent opinion in genetics & development2015

The contribution of specific cell subpopulations to submandibular salivary gland branching morphogenesis.

Hae Ryong Kwon, Melinda Larsen

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development.Developmental dynamics : an official publication of the American Association of Anatomists · 2018
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hae Ryong KwonGraduate Program in Molecular, Cellular, Developmental, and Neural Biology, University at Albany, SUNY, Albany, NY, USA; Department of Biological Sciences, University at Albany, SUNY, Albany, NY, USA.
Melinda LarsenDepartment of Biological Sciences, University at Albany, SUNY, Albany, NY, USA. Electronic address: mlarsen@albany.edu.
University at Albany, State University of New York · US

Funding

Engineering Functional Salivary Glands Using Micropatterned ScaffoldsR01DE022467 · NIDCR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI CASTRACANE, JAMES, LARSEN, MELINDA · 2012 to 2016
$2.4M
Modeling Dynamics of Salivery Gland Branching MorphogenesisR01DE019244 · NIDCR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI LARSEN, MELINDA, YENER, BULENT · 2008 to 2012
$1.5M
Extracellular Scaffold Elasticity and Binding Sites in Acinar DifferentiationR21DE021841 · NIDCR · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI LARSEN, MELINDA · 2012 to 2013
$410k
NIDCR NIH HHS R01 DE019244NIDCR NIH HHS R01DE019244NIDCR NIH HHS R01 DE022467NIDCR NIH HHS R01DE022467NIDCR NIH HHS R21 DE021841NIDCR NIH HHS R21DE02184101
6 · The paper itself

Abstract

Branching morphogenesis is the developmental program responsible for generating a large surface to volume ratio in many secretory and absorptive organs. To accomplish branching morphogenesis, spatiotemporal regulation of specific cell subpopulations is required. Here, we review recent studies that define the contributions of distinct cell subpopulations to specific cellular processes during branching morphogenesis in the mammalian submandibular salivary gland, including the initiation of the gland, the coordination of cleft formation, and the contribution of stem/progenitor cells to morphogenesis. In conclusion, we provide an overview of technological advances that have opened opportunities to further probe the contributions of specific cell subpopulations and to define the integration of events required for branching morphogenesis.

Indexed as

Models, BiologicalAnimalsDevelopmental BiologyMammalsMesodermMorphogenesisSubmandibular Gland

Identifiers

PMID25706196
PMCPMC4470835
OpenAlexW1998240822

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.