Evidence map›Paper›PMID 25706195›Full record

ArticleACS applied materials & interfaces2015

Colloidally stable and surfactant-free protein-coated gold nanorods in biological media.

Moritz Tebbe, Christian Kuttner, Max Männel, Andreas Fery, Munish Chanana

Open access · bronzeAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 176 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Spectroelectrochemical Studies of CTAB Adsorbed on Gold Surfaces in Perchloric Acid.Langmuir : the ACS journal of surfaces and colloids · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Moritz Tebbe†Physical Chemistry II, University of Bayreuth, 95447 Bayreuth, Germany.
Christian Kuttner†Physical Chemistry II, University of Bayreuth, 95447 Bayreuth, Germany.
Max Männel†Physical Chemistry II, University of Bayreuth, 95447 Bayreuth, Germany.
Andreas Fery†Physical Chemistry II, University of Bayreuth, 95447 Bayreuth, Germany.
Munish Chanana†Physical Chemistry II, University of Bayreuth, 95447 Bayreuth, Germany.
University of Bayreuth · DEETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we investigate the ligand exchange of cetyltrimethylammonium bromide (CTAB) with bovine serum albumin for gold nanorods. We demonstrate by surface-enhanced Raman scattering measurements that CTAB, which is used as a shape-directing agent in the particle synthesis, is completely removed from solution and particle surface. Thus, the protein-coated nanorods are suitable for bioapplications, where cationic surfactants must be avoided. At the same time, the colloidal stability of the system is significantly increased, as evidenced by spectroscopic investigation of the particle longitudinal surface plasmon resonance, which is sensitive to aggregation. Particles are stable at very high concentrations (cAu 20 mg/mL) in biological media such as phosphate buffer saline or Dulbecco's Modified Eagle's Medium and over a large pH range (2-12). Particles can even be freeze-dried (lyophilized) and redispersed. The protocol was applied to gold nanoparticles with a large range of aspect ratios and sizes with main absorption frequencies covering the visible and the near-IR spectral range from 600 to 1100 nm. Thus, these colloidally stable and surfactant-free protein-coated nanoparticles are of great interest for various plasmonic and biomedical applications.

Indexed as

AdsorptionCoated Materials, BiocompatibleColloidsDrug StabilityGoldMetal NanoparticlesNanotubesParticle SizeProtein BindingSerum Albumin, BovineSurface-Active AgentsSurface PropertiesCoated Materials, BiocompatibleColloidsGoldSerum Albumin, BovineSurface-Active Agentsbiocompatiblecolloidal stabilityCTAB replacementligand exchangelyophilizedprotein coating

Identifiers

PMID25706195
PMCPMC4476841
OpenAlexW1999325242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.