ArticleBioMed research international2015
Influence of culture media on biofilm formation by Candida species and response of sessile cells to antifungals and oxidative stress.
Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 55 citations in OpenAlex.
- Dental Plaque Removal with Two Special Needs Toothbrushes in Patients with Down Syndrome: A Parallel-Group Randomised Clinical Trial of Efficacy.Oral health & preventive dentistry · 2022Trial
- Influence of environmental and nutritional conditions on Nakaseomyces glabratus biofilm development in vitro.Archives of microbiology · 2026Article
- Distinct properties of human pathogenicmSystems · 2026Article
- Fungal inhibitory activity of sesquiterpenoids isolated fromFrontiers in plant science · 2025Article
- Biofilm production by the multidrug-resistant fungusAIMS microbiology · 2025Article
- Exploring the Complexity of the Interaction betweenMicroorganisms · 2024Article
- Miconazole induces aneuploidy-mediated tolerance inFrontiers in cellular and infection microbiology · 2024Article
- Real-time monitoring of biofilm growth identifies andrographolide as a potent antifungal compound eradicatingBiofilm · 2023Article
- Fungal Glycosidases inJournal of fungi (Basel, Switzerland) · 2023Review
- 2D nanomaterial sensing array using machine learning for differential profiling of pathogenic microbial taxonomic identification.Mikrochimica acta · 2022Article
- Multi-Strain and -Species Investigation of Volatile Metabolites Emitted from Planktonic and BiofilmMetabolites · 2022Article
- Multifactorial Mechanisms of Tolerance to Ketoconazole in Candida albicans.Microbiology spectrum · 2021Article
- The Impact of Cultivation Media on the In Vitro Biofilm Biomass Production of Candida spp.Current microbiology · 2021Article
- Biofilm Formation byFrontiers in microbiology · 2020Article
- Simple Carbohydrate Derivatives Diminish the Formation of Biofilm of the Pathogenic YeastAntibiotics (Basel, Switzerland) · 2019Article
- The use of polyhydroxylated carboxylic acids and lactones to diminish biofilm formation of the pathogenic yeastRSC advances · 2019Article
- Article
- A study on biofilm production and antifungal drug resistance among Candida species from vulvovaginal and bloodstream infections.Infection and drug resistance · 2018Article
- Assessment of herbal drugs for promising anti-Candida activity.BMC complementary and alternative medicine · 2017Article
- Biosynthesis of micro- and nanocrystals of Pb (II), Hg (II) and Cd (II) sulfides in four Candida species: a comparative study of in vivo and in vitro approaches.Microbial biotechnology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims of the study were to evaluate the influence of culture media on biofilm formation by C. albicans, C. glabrata, C. krusei, and C. parapsilosis and to investigate the responses of sessile cells to antifungals and reactive oxygen species (ROS) as compared to planktonic cells. For biofilm formation, the Candida species were grown at different periods of time in YP or YNB media supplemented or not with 0.2 or 2% glucose. Sessile and planktonic cells were exposed to increasing concentrations of antifungals, H2O2, menadione or silver nanoparticles (AgNPs). Biofilms were observed by scanning electron microscopy (SEM) and quantified by the XTT assay. C. albicans formed biofilms preferentially in YPD containing 2% glucose (YPD/2%), C. glabrata in glucose-free YNB or supplemented with 0.2% glucose (YNB/0.2%), while C. krusei and C. parapsilosis preferred YP, YPD/0.2%, and YPD/2%. Interestingly, only C. albicans produced an exopolymeric matrix. This is the first report dealing with the in vitro effect of the culture medium and glucose on the formation of biofilms in four Candida species as well as the resistance of sessile cells to antifungals, AgNPs, and ROS. Our results suggest that candidiasis in vivo is a multifactorial and complex process where the nutritional conditions, the human immune system, and the adaptability of the pathogen should be considered altogether to provide an effective treatment of the patient.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.