Evidence map›Paper›PMID 25705682›Full record

ArticleBioMed research international2015

Anemia in inflammatory bowel disease outpatients: prevalence, risk factors, and etiology.

Carla Valéria de Alvarenga Antunes, Abrahão Elias Hallack Neto, Cristiano Rodrigo de Alvarenga Nascimento, Liliana Andrade Chebli, Ivana Lúcia Damásio Moutinho, Bruno do Valle Pinheiro, Maycon Moura Reboredo, Carla Malaguti, Antonio Carlos Santana Castro, Júlio Maria Fonseca Chebli

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02760940 (Anemia Treatment in Inflammatory Bowel Disease), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02760940 phase4unknown statusnot on this mapstarted 2016, after this paper: background citation

Anemia Treatment in Inflammatory Bowel Disease: Predictive Factors of Response to Oral Iron Treatment

TypeinterventionalSponsorFederal University of Juiz de ForaRan2016 to 2018Enrolled200ConditionsAnemia, Bowel Diseases, InflammatoryArmsoral liposomal iron
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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  6. Calprotectin in inflammatory bowel disease.Clinica chimica acta; international journal of clinical chemistry · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Carla Valéria de Alvarenga AntunesDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Abrahão Elias Hallack NetoDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Cristiano Rodrigo de Alvarenga NascimentoDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Liliana Andrade ChebliDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Ivana Lúcia Damásio MoutinhoDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Bruno do Valle PinheiroDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Maycon Moura ReboredoDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Carla MalagutiDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Antonio Carlos Santana CastroDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Júlio Maria Fonseca ChebliDivision of Gastroenterology, Department of Medicine, Inflammatory Bowel Diseases Center, University Hospital of the Federal University of Juiz de Fora, University of Juiz de Fora School of Medicine, Avenida Eugênio do Nascimento s/n°, Dom Bosco, 36038-330 Juiz de Fora, MG, Brazil.
Universidade Federal de Juiz de Fora · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledAnemia is common in inflammatory bowel disease (IBD). However, epidemiological studies of nonwestern IBD populations are limited and may be confounded by demographic, socioeconomic, and disease-related influences. This study evaluated the prevalence, risk factors, and etiology of anemia in Brazilian outpatients with IBD.

methodsIn this cross-sectional study, 100 Crohn's disease (CD) patients and 100 ulcerative colitis (UC) subjects were assessed. Anemia workup included complete blood count, ferritin, transferrin saturation, serum levels of folic acid and vitamin B12, and C-reactive protein (CRP) concentration.

resultsThe overall prevalence of anemia in IBD was 21%. There was no significant difference in the prevalence of anemia between CD subjects (24%) and UC (18%). Moderate disease activity (OR: 3.48, 95% CI, 1.95-9.64, P = 0.002) and elevated CRP levels (OR: 1.8, 95% CI, 1.04-3.11, P = 0.02) were independently associated with anemia. The most common etiologies of anemia found in both groups were iron deficiency anemia (IDA; 10% on CD and 6% on UC) followed by the anemia of chronic disease (ACD; 6% for both groups).

conclusionsIn Brazilian IBD outpatients, anemia is highly concurrent condition. Disease moderate activity as well as increased CRP was strongly associated with comorbid anemia. IDA and/or ACD were the most common etiologies.

Indexed as

AdolescentAdultAgedAnemiaBlood Cell CountBrazilC-Reactive ProteinFemaleFerritinsFolic AcidHumansInflammatory Bowel DiseasesMaleMiddle AgedOutpatientsRisk FactorsC-Reactive ProteinFerritinsFolic AcidTransferrinVitamin B 12

Identifiers

PMID25705682
PMCPMC4331158
OpenAlexW2032275878

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.