ReviewBioMed research international2015
Novel insights on nutrient management of sarcopenia in elderly.
Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02402608 (Whey Protein, Amino Acids and Vitamin D Supplementation With Physical Activity Increases Muscle Mass and Strength, Functionality and Quality of Life and Decreases Inflammation in Sarcopenic Elderly), which is not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Whey Protein, Amino Acids and Vitamin D Supplementation With Physical Activity Increases Muscle Mass and Strength, Functionality and Quality of Life and Decreases Inflammation in Sarcopenic Elderly
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Mediterranean Diet and Musculoskeletal-Functional Outcomes in Community-Dwelling Older People: A Systematic Review and Meta-Analysis.The journal of nutrition, health & aging · 2018Pooled it
- Effects of 12 Weeks of Essential Amino Acids (EAA)-Based Multi-Ingredient Nutritional Supplementation on Muscle Mass, Muscle Strength, Muscle Power and Fatigue in Healthy Elderly Subjects: A Randomized Controlled Double-Blind Study.The journal of nutrition, health & aging · 2019Trial
- The association between healthy beverage index and sarcopenia in Iranian older adults: a case-control study.BMC geriatrics · 2024Article
- A Machine-Learning Approach to Target Clinical and Biological Features Associated with Sarcopenia: Findings from Northern and Southern Italian Aging Populations.Metabolites · 2023Article
- The beneficial therapeutic effects of plant-derived natural products for the treatment of sarcopenia.Journal of cachexia, sarcopenia and muscle · 2022Review
- Assessing the Effects of Dietary Protein Supplementation on Sarcopenia in Community-Dwelling Older Adults.Canadian geriatrics journal : CGJ · 2022Review
- Article
- Cottonseed Meal Protein Isolate as a New Source of Alternative Proteins: A Proteomics Perspective.International journal of molecular sciences · 2022Article
- Benefits and Risks Associated with Meat Consumption during Key Life Processes and in Relation to the Risk of Chronic Diseases.Foods (Basel, Switzerland) · 2022Review
- Association Between Serum Iron Status and Muscle Mass in Adults: Results From NHANES 2015-2018.Frontiers in nutrition · 2022Article
- Malnutrition, assessed by the Global Leadership Initiative on Malnutrition (GLIM) criteria but not by the mini nutritional assessment (MNA), predicts the incidence of sarcopenia over a 5-year in the SarcoPhAge cohort.Aging clinical and experimental research · 2021Article
- Chronic Critical Illness and PICS Nutritional Strategies.Journal of clinical medicine · 2021Review
- Sarcopenia in Inflammatory Bowel Disease: A Narrative Overview.Nutrients · 2021Review
- Patterns of Nutrient Intake in Relation to Sarcopenia and Its Components.Frontiers in nutrition · 2021Article
- Association between Changes in Nutrient Intake and Changes in Muscle Strength and Physical Performance in the SarcoPhAge Cohort.Nutrients · 2020Article
- Chronic Critical Illness Patients Fail to Respond to Current Evidence-Based Intensive Care Nutrition Secondarily to Persistent Inflammation, Immunosuppression, and Catabolic Syndrome.JPEN. Journal of parenteral and enteral nutrition · 2020Article
- Future of Chondroprotectors in the Treatment of Degenerative Processes of Connective Tissue.Pharmaceuticals (Basel, Switzerland) · 2020Review
- Association of Serum Amino Acid Concentration With Loss of Skeletal Muscle Mass After 1 Year in Cardiac Rehabilitation Center Patients.Circulation reports · 2019Article
- Review
- Amino acids and amino acid sensing: implication for aging and diseases.Biogerontology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenia is defined as a syndrome characterized by progressive and generalized loss of muscle mass and strength. The more rationale approach to delay the progression of sarcopenia is based on the combination of proper nutrition, possibly associated with the use of dietary supplements and a regular exercise program. We performed a narrative literature review to evaluate the till-now evidence regarding (1) the metabolic and nutritional correlates of sarcopenia; (2) the optimum diet therapy for the treatment of these abnormalities. This review included 67 eligible studies. In addition to the well recognized link between adequate intake of proteins/amino acids and sarcopenia, the recent literature underlines that in sarcopenic elderly subjects there is an unbalance in vitamin D synthesis and in omega-6/omega-3 PUFA ratio. Given the detrimental effect of these metabolic abnormalities, a change in the lifestyle must be the cornerstone in the treatment of sarcopenia. The optimum diet therapy for the sarcopenia treatment must aim at achieving specific metabolic goals, which must be reached through accession of the elderly to specific personalized dietary program aimed at achieving and/or maintaining muscle mass; increasing their intake of fish (4 times/week) or taking omega-3 PUFA supplements; taking vitamin D supplementation, if there are low serum levels.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.