Evidence map›Paper›PMID 25705660›Full record

ArticleBioMed research international2015

Transcriptional and biochemical effects of cadmium and manganese on the defense system of Octopus vulgaris paralarvae.

Aldo Nicosia, Monica Salamone, Salvatore Mazzola, Angela Cuttitta

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Stress Induced by Fishing in Common Octopus (Animals : an open access journal from MDPI · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aldo NicosiaLaboratory of Molecular Ecology and Biotechnology, National Research Council, Institute for Coastal Marine Environment, UOS Capo Granitola, Torretta Granitola, 91021 Trapani, Italy.ORCID 0000-0003-1722-2155
Monica SalamoneLaboratory of Molecular Ecology and Biotechnology, National Research Council, Institute for Coastal Marine Environment, UOS Capo Granitola, Torretta Granitola, 91021 Trapani, Italy.
Salvatore MazzolaNational Research Council, Institute for Coastal Marine Environment, Calata Porta di Massa, 80133 Naples, Italy.
Angela CuttittaLaboratory of Molecular Ecology and Biotechnology, National Research Council, Institute for Coastal Marine Environment, UOS Capo Granitola, Torretta Granitola, 91021 Trapani, Italy.
Institute for Coastal Marine Environment · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to anthropogenic activities the relative concentrations of cadmium and manganese have increased in the marine environment. Cephalopods are able to accumulate such metals and, as inhabitant of coastal waters, Octopus vulgaris is continuously exposed to anthropogenic activities. Since no study is available on the effects of heavy metals at molecular level in developing octopuses, herein we exposed 1-day-old paralarvae for 24 h to 10, 100, and 1000 μg/L of CdCl2 or MnCl2. Cd exerted a concentration-dependent inhibition of survival and a reduction in growth rate was shown while Mn exposure did not affect the survival rate even at the highest concentrations. Gene expression profiles of hsp70, sod, cat, and gst genes were analyzed by quantitative real-time PCR and defined patterns of transcription were observed. Moreover posttranscriptional analyses were also performed suggesting the impairment of metabolic functions, under strong oxidative conditions (as occurred in paralarvae exposed to Cd) or the complete detoxification events (as occurred in paralarvae exposed to Mn).

Indexed as

AnimalsCadmiumCatalaseEnvironmental ExposureGene Expression RegulationGlutathione TransferaseHSP70 Heat-Shock ProteinsHumansManganeseOctopodiformesSuperoxide DismutaseTranscriptomeCadmiumCatalaseGlutathione TransferaseHSP70 Heat-Shock ProteinsManganeseSuperoxide Dismutase

Identifiers

PMID25705660
PMCPMC4326271
OpenAlexW2042265097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.