ArticleCurrent sleep medicine reports2015
Myoclonic Twitching and Sleep-Dependent Plasticity in the Developing Sensorimotor System.
Article in Current sleep medicine reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 62 citations in OpenAlex.
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- Manual and automated assessments of general movements in neonates are associated with early autism risk at 18 months.Scientific reports · 2026Article
- Understanding Sleep Regulation in Normal and Pathological Conditions, and Why It Matters.Journal of Huntington's disease · 2023Review
- Relations between sleep patterns early in life and brain development: A review.Developmental cognitive neuroscience · 2022Review
- Reconciling competing mechanisms posited to underlie auditory verbal hallucinations.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Article
- Early movement restriction leads to enduring disorders in muscle and locomotion.Brain pathology (Zurich, Switzerland) · 2018Article
- Theta Oscillations during Active Sleep Synchronize the Developing Rubro-Hippocampal Sensorimotor Network.Current biology : CB · 2017Article
- The Nature of the Sensory Input to the Neonatal Rat Barrel Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
As bodies grow and change throughout early development and across the lifespan, animals must develop, refine, and maintain accurate sensorimotor maps. Here we review evidence that myoclonic twitches-brief and discrete contractions of the muscles, occurring exclusively during REM (or active) sleep, that result in jerks of the limbs-help animals map their ever-changing bodies by activating skeletal muscles to produce corresponding sensory feedback, or reafference. First, we highlight the spatiotemporal characteristics of twitches. Second, we review findings in infant rats regarding the multitude of brain areas that are activated by twitches during sleep. Third, we discuss evidence demonstrating that the sensorimotor processing of twitches is different from that of wake movements; this state-related difference in sensorimotor processing provides perhaps the strongest evidence yet that twitches are uniquely suited to drive certain aspects of sensorimotor development. Finally, we suggest that twitching may help inform our understanding of neurodevelopmental disorders, perhaps even providing opportunities for their early detection and treatment.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.