ArticleCurrent environmental health reports2014
Environmental Health Factors and Sexually Dimorphic Differences in Behavioral Disruptions.
Article in Current environmental health reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Sex Differences in Seasonal Variation in Metabolic Syndrome and Its Components: A 10-Year National Health Screening Study.Journal of clinical medicine · 2025Article
- Review
- Should Pregnant Women Consume Probiotics to Combat Endocrine-Disrupting Chemical-Induced Health Risks to Their Unborn Offspring?Biomedicines · 2024Review
- Epigenome-Wide Associations of Placental DNA Methylation and Behavioral and Emotional Difficulties in Children at 3 Years of Age.International journal of molecular sciences · 2023Article
- Associations between infant sex and DNA methylation across umbilical cord blood, artery, and placenta samples.Epigenetics · 2022Article
- Sex-specific effects of bisphenol A on the signaling pathway of ESRRG in the human placenta†.Biology of reproduction · 2022Article
- Article
- Disruption of global hypothalamic microRNA (miR) profiles and associated behavioral changes in California mice (Peromyscus californicus) developmentally exposed to endocrine disrupting chemicals.Hormones and behavior · 2021Article
- Bisphenol A, S or F mother's dermal impregnation impairs offspring immune responses in a dose and sex-specific manner in mice.Scientific reports · 2021Article
- Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies.Reproductive toxicology (Elmsford, N.Y.) · 2020Article
- A role for microRNAs in the epigenetic control of sexually dimorphic gene expression in the human placenta.Epigenomics · 2020Article
- Sex and poverty modify associations between maternal peripartum concentrations of DDT/E and pyrethroid metabolites and thyroid hormone levels in neonates participating in the VHEMBE study, South Africa.Environment international · 2019Article
- Social and neuromolecular phenotypes are programmed by prenatal exposures to endocrine-disrupting chemicals.Molecular and cellular endocrinology · 2019Article
- Current Knowledge on Endocrine Disrupting Chemicals (EDCs) from Animal Biology to Humans, from Pregnancy to Adulthood: Highlights from a National Italian Meeting.International journal of molecular sciences · 2018Review
- Prenatal Mancozeb Exposure, Excess Manganese, and Neurodevelopment at 1 Year of Age in the Infants' Environmental Health (ISA) Study.Environmental health perspectives · 2018Article
- Mate choice, sexual selection, and endocrine-disrupting chemicals.Hormones and behavior · 2018Review
- Exposure to extrinsic stressors, social defeat or bisphenol A, eliminates sex differences in DNA methyltransferase expression in the amygdala.Journal of neuroendocrinology · 2017Article
- Review
- Perinatal exposure to endocrine disruptors: sex, timing and behavioral endpoints.Current opinion in behavioral sciences · 2016Article
- Sex-dependent effects of developmental exposure to bisphenol A and ethinyl estradiol on metabolic parameters and voluntary physical activity.Journal of developmental origins of health and disease · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Mounting evidence suggests that environmental factors-in particular, those that we are exposed to during perinatal life-can dramatically shape the organism's risk for later diseases, including neurobehavioral disorders. However, depending on the environmental insult, one sex may demonstrate greater vulnerability than the other sex. Herein, we focus on two well-defined extrinsic environmental factors that lead to sexually dimorphic behavioral differences in animal models and linkage in human epidemiological studies. These include maternal or psychosocial stress (such as social stress) and exposure to endocrine-disrupting compounds (such as one of the most prevalent, bisphenol A [BPA]). In general, the evidence suggests that early environmental exposures, such as BPA and stress, lead to more pronounced behavioral deficits in males than in females, whereas female neurobehavioral patterns are more vulnerable to later in life stress. These findings highlight the importance of considering sex differences and developmental timing when examining the effects of environmental factors on later neurobehavioral outcomes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.