Evidence map›Paper›PMID 25705579›Full record

ArticleCurrent behavioral neuroscience reports2014

Looking beyond Fear and Extinction Learning: Considering Novel Treatment Targets for Anxiety.

Jennifer C Britton, Travis C Evans, Michael V Hernandez

Abstract read
In one paragraph

Article in Current behavioral neuroscience reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer C BrittonDepartment of Psychology, University of Miami.
Travis C EvansDepartment of Psychology, University of Miami.
Michael V HernandezDepartment of Psychology, University of Miami.

Funding

Neuroimaging of Extinction Recall in Development and Adolescent Social AnxietyR00MH091183 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI BRITTON, JENNIFER CHRISTINA · 2012 to 2014
$708k
NIMH NIH HHS R00 MH091183
6 · The paper itself

Abstract

Fear conditioning studies provide valuable insight into how fears are learned and extinguished. Previous work focuses on fear and extinction learning to understand and treat anxiety disorders. However, a cascade of cognitive processes that extend beyond learning may also yield therapeutic targets for anxiety disorders. Throughout this review, we will discuss recent findings of fear generalization, memory consolidation, and reconsolidation. Factors related to effectiveness, efficiency and durability of extinction-based treatments will be addressed. Moreover, adolescence may be a key developmental stage when threat-related perturbations emerge; therefore, targeting interventions during adolescence when these nascent processes are more malleable may alter the trajectory of anxiety disorders.

Indexed as

adolescenceamygdalaanxietyconsolidationfear conditioningfunctional magnetic resonance imaginggeneralizationhippocampushumanprefrontal cortexreconsolidationsleep

Identifiers

PMID25705579
PMCPMC4333677

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.