ArticleChemical science2015
Development and Investigation of a Site Selective Palladium-Catalyzed 1,4-Difunctionalization of Isoprene using Pyridine-Oxazoline Ligands.
Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Catalytic Asymmetric 1,2-Migration/Allylation of Alkynyl Boronate Complexes: A Modular Route to Enantioenriched Skipped 1,4-Dienes.Journal of the American Chemical Society · 2026Article
- Reductive coupling of allenyl/allyl carbonate with alkyne under dual cobalt-photoredox catalysis.Nature communications · 2024Article
- Stereoselectivity Predictions for the Pd-Catalyzed 1,4-Conjugate Addition Using Quantum-Guided Molecular Mechanics.The Journal of organic chemistry · 2021Article
- Regioselective Arylboration of 1,3-Butadiene.Israel journal of chemistry · 2020Article
- Pyridine(diimine) Iron Diene Complexes Relevant to Catalytic [2+2]-Cycloaddition Reactions.Advanced synthesis & catalysis · 2020Article
- Nickel-Catalyzed Stereoselective Diarylation of Alkenylarenes.Journal of the American Chemical Society · 2018Article
- Copper-catalyzed enantioselective 1,2-borylation of 1,3-dienes.Chemical science · 2018Article
- Copper-Catalyzed Heteroarylboration of 1,3-Dienes with 3-Bromopyridines: A cine Substitution.Angewandte Chemie (International ed. in English) · 2018Article
- Second-Generation Palladium Catalyst System for Transannular C-H Functionalization of Azabicycloalkanes.Journal of the American Chemical Society · 2018Article
- Catalyst Controlled Regiodivergent Arylboration of Dienes.Journal of the American Chemical Society · 2017Article
- Regioselective Arylboration of Isoprene and Its Derivatives by Pd/Cu Cooperative Catalysis.Journal of the American Chemical Society · 2017Article
- The development and mechanistic investigation of a palladium-catalyzed 1,3-arylfluorination of chromenes.Chemical science · 2017Article
- Rhodium-Catalyzed Hydrofunctionalization: Enantioselective Coupling of Indolines and 1,3-Dienes.Journal of the American Chemical Society · 2017Article
- Mechanism and Selectivity in the Pd-Catalyzed Difunctionalization of Isoprene.The Journal of organic chemistry · 2016Article
- Palladium-Catalyzed 1,3-Difunctionalization Using Terminal Alkenes with Alkenyl Nonaflates and Aryl Boronic Acids.Organic letters · 2016Article
- Enantiodivergent Fluorination of Allylic Alcohols: Data Set Design Reveals Structural Interplay between Achiral Directing Group and Chiral Anion.Journal of the American Chemical Society · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Palladium-catalyzed 1,4-difunctionalizations of isoprene that produce skipped polyenes are reported. Complex isomeric product mixtures are possible as a result of the difficult-to-control migratory insertion of isoprene into a Pd-alkenyl bond, but good site selectivity has been achieved using easily accessible Pyrox ligands. Mechanistic studies suggest that the control of insertion is the result of the unique electronic asymmetry and steric properties of the ligand.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.