Evidence map›Paper›PMID 25705232›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2015

Insights and advances in chronic urticaria: a Canadian perspective.

Gordon Sussman, Jacques Hébert, Wayne Gulliver, Charles Lynde, Susan Waserman, Amin Kanani, Moshe Ben-Shoshan, Spencer Horemans, Carly Barron, Stephen Betschel and 8 more

Open access · goldAbstract read
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Comorbidities in Canadian patients with hereditary angioedema: a quantitative survey study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  3. Urticaria.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Review
  4. Article
  5. Adverse cutaneous reactions after mRNA SARS-CoV-2 vaccination in 3 patients: a spectrum of severity.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022
    Article
  6. Article
  7. Refractory chronic urticaria in adults: clinical characterization and predictors of severity.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020
    Article
  8. Serum Levels of Eosinophil-derived Neurotoxin in Patients with Chronic Urticaria.The Journal of clinical and aesthetic dermatology · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. CSACI position statement: Newer generation HAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019
    Review
  14. Article
  15. Urticaria and angioedema.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018
    Review
  16. Article
  17. Management of chronic spontaneous urticaria (CSU): a treat to target approach using a patient reported outcome.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2017
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 1 country.

Gordon SussmanUniversity of Toronto, Medicine, Toronto, ON Canada.
Jacques HébertUniversité Laval, Medicine, Quebec, QC Canada.
Wayne GulliverMemorial University, Medicine, Quebec, QC Canada.
Charles LyndeUniversity of Toronto, Medicine, Toronto, ON Canada.
Susan WasermanMcMaster University Medicine, Hamilton, ON Canada.
Amin KananiUniversity of British Columbia, Medicine, Kelowna, BC Canada.
Moshe Ben-ShoshanMcGill University, Medicine, Montreal, QC Canada.
Spencer HoremansUniversity of Toronto, Medicine, Toronto, ON Canada.
Carly BarronUniversity of Toronto, Medicine, Toronto, ON Canada.
Stephen BetschelUniversity of Toronto, Medicine, Toronto, ON Canada.
William H YangUniversity of Ottawa, Medicine, Ottawa, ON Canada.
Jan DutzUniversity of British Columbia, Medicine, Kelowna, BC Canada.
Neil ShearUniversity of Toronto, Medicine, Toronto, ON Canada.
Gina LacuestaDalhousie University, Medicine, Halifax, NS Canada.
Peter VadasUniversity of Toronto, Medicine, Toronto, ON Canada.
Kenneth KobayashiUniversity of Ottawa, Medicine, Ottawa, ON Canada.
Hermenio LimaMcMaster University Medicine, Hamilton, ON Canada.
F Estelle R SimonsUniversity of Manitoba, Medicine, Winnipeg, MB Canada.
University of Toronto · CAMcMaster University · CAUniversity of Ottawa · CADalhousie University · CAKelowna General Hospital · CAMcGill University · CAMemorial University of Newfoundland · CAUniversité Laval · CAUniversity of British Columbia · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past few years there have been significant advances which have changed the face of chronic urticaria. In this review, we aim to update physicians about clinically relevant advances in the classification, diagnosis and management of chronic urticaria that have occurred in recent years. These include clarification of the terminology used to describe and classify urticaria. We also detail the development and validation of instruments to assess urticaria and understand the impairment on quality-of-life and the morbidity caused by this disease. Additionally, the approach to management of chronic urticaria now focuses on evidence-based use of non-impairing, non-sedating H1-antihistamines given initially in standard doses and if this is not effective, in up to 4-fold doses. For urticaria refractory to H1-antihistamines, omalizumab treatment has emerged as an effective, safe option.

Indexed as

AntihistaminesChronic urticariaClassificationDiagnosisImmunologyManagementOmalizumabUp-dosing

Identifiers

PMID25705232
PMCPMC4336710
OpenAlexW2131291377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.