ArticleNeuron2015
Spontaneous neuronal network dynamics reveal circuit's functional adaptations for behavior.
Article in Neuron, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed.
- Article
- Anti-NMDAR encephalitis impairs intrinsic hippocampal dynamics through neuronal hypercoupling, hub dominance, and aberrant ensembles.Molecular psychiatry · 2026Article
- Canalization of neural dynamics by δ-protocadherins in the developing zebrafish optic tectum.PLoS genetics · 2026Article
- Spatial Subdomains in the Optic Tectum for the Encoding of Visual Information.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Topological analysis of neuronal assemblies reveals low-rank structure modulated by cholinergic activity.bioRxiv : the preprint server for biology · 2025Article
- Designed optogenetic tool for bridging single-neuronal multimodal information in intact animals.Nature communications · 2025Article
- Noise correlations and neuronal diversity may limit the utility of winner-take-all readout in a pop out visual search task.PLoS computational biology · 2025Article
- A detailed quantification of larval zebrafish behavioral repertoire uncovers principles of hunting behavior.iScience · 2025Article
- Canalization of circuit assembly by δ-protocadherins in the zebrafish optic tectum.bioRxiv : the preprint server for biology · 2025Article
- Article
- High-resolution tracking of unconfined zebrafish behavior reveals stimulatory and anxiolytic effects of psilocybin.Molecular psychiatry · 2024Article
- Simultaneous, cortex-wide and cellular-resolution neuronal population dynamics reveal an unbounded scaling of dimensionality with neuron number.bioRxiv : the preprint server for biology · 2024Article
- Radial astrocyte synchronization modulates the visual system during behavioral-state transitions.Neuron · 2023Article
- A synaptic corollary discharge signal suppresses midbrain visual processing during saccade-like locomotion.Nature communications · 2023Article
- Microscale Neuronal Activity Collectively Drives Chaotic and Inflexible Dynamics at the Macroscale in Seizures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Neural Ensemble Fragmentation in the AnesthetizedThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Recurrent network interactions explain tectal response variability and experience-dependent behavior.eLife · 2023Article
- From perception to behavior: The neural circuits underlying prey hunting in larval zebrafish.Frontiers in neural circuits · 2023Review
- Topographically Localized Modulation of Tectal Cell Spatial Tuning by Complex Natural Scenes.eNeuro · 2023Article
- Network instability dynamics drive a transient bursting period in the developing hippocampus in vivo.eLife · 2022Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Spontaneous neuronal activity is spatiotemporally structured, influencing brain computations. Nevertheless, the neuronal interactions underlying these spontaneous activity patterns, and their biological relevance, remain elusive. Here, we addressed these questions using two-photon calcium imaging of intact zebrafish larvae to monitor the neuron-to-neuron spontaneous activity fine structure in the tectum, a region involved in visual spatial detection. Spontaneous activity was organized in topographically compact assemblies, grouping functionally similar neurons rather than merely neighboring ones, reflecting the tectal retinotopic map despite being independent of retinal drive. Assemblies represent all-or-none-like sub-networks shaped by competitive dynamics, mechanisms advantageous for visual detection in noisy natural environments. Notably, assemblies were tuned to the same angular sizes and spatial positions as prey-detection performance in behavioral assays, and their spontaneous activation predicted directional tail movements. Therefore, structured spontaneous activity represents "preferred" network states, tuned to behaviorally relevant features, emerging from the circuit's intrinsic non-linear dynamics, adapted for its functional role.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.