ArticlePaediatrics and international child health2016
Antimicrobial susceptibility of uropathogens isolated from Cambodian children.
Article in Paediatrics and international child health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 39 citations in OpenAlex.
- Etiological and Resistance Profile of Bacteria Involved in Urinary Tract Infections in Young Children.BioMed research international · 2017Trial
- Antimicrobial susceptibility profiles of invasive bacterial infections among children from low- and middle-income countries in the Western Pacific Region (WPRO) - a systematic review and meta-analysis.The Lancet regional health. Western Pacific · 2024Article
- Phenotypic characterization of ESBL-producing urinary isolates of E. coli and Klebsiella spp. in a tertiary care children's hospital in Nepal.Tropical medicine and health · 2024Article
- Retrospective 8-Year Study on the Antibiotic Resistance of Uropathogens in Children Hospitalised for Urinary Tract Infection in the Emilia-Romagna Region, Italy.Antibiotics (Basel, Switzerland) · 2021Article
- Epidemiology of Extended-Spectrum Beta-Lactamase and Carbapenemase-Producing Enterobacterales in the Greater Mekong Subregion: A Systematic-Review and Meta-Analysis of Risk Factors Associated With Extended-Spectrum Beta-Lactamase and Carbapenemase Isolation.Frontiers in microbiology · 2021Review
- Extended-spectrum beta-lactamaseEpidemiology and infection · 2020Article
- Prevalence of MDR organism (MDRO) carriage in children and their household members in Siem Reap Province, Cambodia.JAC-antimicrobial resistance · 2020Article
- Enhanced quantitative urine culture technique, a slight modification, in detecting under-diagnosed pediatric urinary tract infection.BMC research notes · 2020Article
- Extended-SpectrumInterdisciplinary perspectives on infectious diseases · 2020Article
- Carriage of carbapenemase- and extended-spectrum cephalosporinase-producing Escherichia coli and Klebsiella pneumoniae in humans and livestock in rural Cambodia; gender and age differences and detection of blaZoonoses and public health · 2019Article
- Epidemiology of paediatric gastrointestinal colonisation by extended spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates in north-west Cambodia.BMC microbiology · 2019Article
- Frequency of Uropathogens and Antimicrobial Susceptibility in Childhood Urinary Tract Infection at Kamenge University Hospital, Bujumbura, Burundi.The East African health research journal · 2017Article
- High rates of multidrug resistance among uropathogenicAntimicrobial resistance and infection control · 2017Article
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBacterial resistance to commonly used antimicrobials is an increasing problem in Asia but information concerning the antimicrobial susceptibility of bacteria causing urinary tract infections (UTIs) in children is limited.
methodsThis was a 5-year retrospective study of children with suspected UTI attending a paediatric hospital in north-west Cambodia. Urines with a positive culture containing a single organism with a count of >10(5) colony-forming units (CFU)/ml were considered diagnostic of infection. The organism was identified and the resistance pattern (using CLSI guidelines) and presence of an extended-spectrum β-lactamase (ESBL) phenotype was determined.
resultsIn total, there were 217 episodes of infection, 210 (97%) with Gram-negative bacteria. Escherichia coli was the most common infecting isolate with high levels of resistance to most oral antibiotics, except nitrofurantoin. Nearly half of the E. coli (44%) were extended-spectrum cephalosporin (ESC)-resistant with the proportion increasing significantly over the 5-year period. ESC-resistant E. coli were more likely to be multi-drug-resistant and 91% demonstrated an ESBL phenotype.
conclusionThe data highlight the importance of microbiological surveillance of UTIs in children, particularly in areas where there are known to be multiply resistant organisms.
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