ReviewSeminars in nuclear medicine2015
Evaluation of hypoxia with copper-labeled diacetyl-bis(N-methylthiosemicarbazone).
Review in Seminars in nuclear medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Article
- Emerging Nuclear Medicine Imaging of Atherosclerotic Plaque Formation.Journal of imaging · 2022Review
- Oxidative stress in multiple sclerosis-Emerging imaging techniques.Frontiers in neurology · 2022Review
- Expanding the PET radioisotope universe utilizing solid targets on small medical cyclotrons.RSC advances · 2021Review
- Leveraging copper import by yersiniabactin siderophore system for targeted PET imaging of bacteria.JCI insight · 2021Article
- Review
- Toward noninvasive quantification of adipose tissue oxygenation with MRI.International journal of obesity (2005) · 2020Article
- Applications for Transition-Metal Chemistry in Contrast-Enhanced Magnetic Resonance Imaging.Inorganic chemistry · 2020Review
- Copper promotion of myocardial regeneration.Experimental biology and medicine (Maywood, N.J.) · 2020Review
- Hypoxia imaging and theranostic potential of [EJNMMI research · 2020Review
- Monte Carlo Evaluation of Dose Enhancement Due to CuATSM or GNP Uptake in Hypoxic Environments with External Beam Radiation.International journal of nanomedicine · 2020Article
- Molecular Imaging of Inflammation in a Mouse Model of Atherosclerosis Using a Zirconium-89-Labeled Probe.International journal of nanomedicine · 2020Article
- Impact of [BMC cancer · 2019Article
- How clinical imaging can assess cancer biology.Insights into imaging · 2019Review
- Highly sensitive electron paramagnetic resonance nanoradicals for quantitative intracellular tumor oxymetric images.International journal of nanomedicine · 2019Article
- Uniform intratumoral distribution of radioactivity produced using two different radioagents,EJNMMI research · 2018Article
- Theranostic Probes for Targeting Tumor Microenvironment: An Overview.International journal of molecular sciences · 2017Review
- Opportunities and challenges for metal chemistry in molecular imaging: from gamma camera imaging to PET and multimodality imaging.Advances in inorganic chemistry · 2016Article
- Correlation between imaging and tissue biomarkers of hypoxia in squamous cell cancer of the head and neck.World journal of nuclear medicineArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Imaging of hypoxia is important in many diseases states in oncology, cardiology, and neurology. The radiopharmaceutical, copper-labeled diacetyl-bis(N-methylthiosemicarbazone), has been used to assess hypoxia in many studies. In particular, copper-labeled diacetyl-bis(N-methylthiosemicarbazone) has been used in oncologic settings to investigate tumor hypoxia and the role of this parameter in response to therapy and outcome. Some groups have conducted imaging studies assessing the role of hypoxia in cardiovascular and neurologic disorders. Additionally, several groups have made significant progress into understanding the mechanism by which this compound accumulates in cells. Multiple preclinical and clinical studies have been conducted, shedding light on the importance of careful image analysis when using this tracer. This review article focuses on the recent preclinical and clinical studies with this tracer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.