Evidence map›Paper›PMID 25704218›Full record

ArticleJournal of cataract and refractive surgery2015

Dynamic imaging of accommodation by swept-source anterior segment optical coherence tomography.

Alberto Neri, Marco Ruggeri, Alessandra Protti, Rosachiara Leaci, Stefano A Gandolfi, Claudio Macaluso

Open access · greenAbstract read
In one paragraph

Article in Journal of cataract and refractive surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 52 citations in OpenAlex.

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  12. Do Gender, Age, Body Mass and Height Influence Eye Biometrical Properties in Young Adults? A Pilot Study.International journal of environmental research and public health · 2021
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  16. Comparison of anterior segment and lens biometric measurements in patients with cataract.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alberto NeriOphthalmology Department (Neri, Protti, Leaci, Gandolfi, Macaluso), Dipartimento di Scienze Biomediche, Biotecnologiche e Traslazionali, University of Parma, Parma, Italy; the Ophthalmic Biophysics Center (Ruggeri), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA. Electronic address: neri.mail2@gmail.com.
Marco RuggeriOphthalmology Department (Neri, Protti, Leaci, Gandolfi, Macaluso), Dipartimento di Scienze Biomediche, Biotecnologiche e Traslazionali, University of Parma, Parma, Italy; the Ophthalmic Biophysics Center (Ruggeri), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Alessandra ProttiOphthalmology Department (Neri, Protti, Leaci, Gandolfi, Macaluso), Dipartimento di Scienze Biomediche, Biotecnologiche e Traslazionali, University of Parma, Parma, Italy; the Ophthalmic Biophysics Center (Ruggeri), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Rosachiara LeaciOphthalmology Department (Neri, Protti, Leaci, Gandolfi, Macaluso), Dipartimento di Scienze Biomediche, Biotecnologiche e Traslazionali, University of Parma, Parma, Italy; the Ophthalmic Biophysics Center (Ruggeri), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Stefano A GandolfiOphthalmology Department (Neri, Protti, Leaci, Gandolfi, Macaluso), Dipartimento di Scienze Biomediche, Biotecnologiche e Traslazionali, University of Parma, Parma, Italy; the Ophthalmic Biophysics Center (Ruggeri), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
Claudio MacalusoOphthalmology Department (Neri, Protti, Leaci, Gandolfi, Macaluso), Dipartimento di Scienze Biomediche, Biotecnologiche e Traslazionali, University of Parma, Parma, Italy; the Ophthalmic Biophysics Center (Ruggeri), Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida, USA.
University of Miami · US

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
Optomechanical charactristics of lens accommodationR01EY014225 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MANNS, FABRICE · 2002 to 2019
$5.5M
Optics of the Growing Crystalline LensR01EY021834 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI MANNS, FABRICE · 2012 to 2016
$2.3M
NEI NIH HHS 2R01EY14225NEI NIH HHS P30 EY014801NEI NIH HHS P30EY14801NEI NIH HHS R01 EY014225NEI NIH HHS R01 EY021834NEI NIH HHS R01EY021834
6 · The paper itself

Abstract

purposeTo study the accommodation process in normal eyes using a commercially available clinical system based on swept-source anterior segment optical coherence tomography (AS-OCT).

settingOphthalmology Department, University of Parma, Italy.

designEvaluation of diagnostic technology.

methodsRight eyes were analyzed using swept-source AS-OCT (Casia SS-1000). The optical vergence of the internal coaxial fixation target was adjusted during imaging to obtain monocular accommodation stimuli with different amplitudes (0, 3.0, 6.0, and 9.0 diopters [D]). Overlapping of real and conjugate OCT images enabled imaging of all the anterior segment optical surfaces in a single frame. Central corneal thickness (CCT), anterior chamber depth (ACD), and lens thickness were extracted from the OCT scans acquired at different static accommodation stimulus amplitudes. The crystalline lens was analyzed dynamically during accommodation and disaccommodation by acquiring sequential OCT images of the anterior segment at a rate of 8 frames per second. The lens thickness was extracted from the temporal sequence of OCT images and plotted as a function of time.

resultsThe study analyzed 14 eyes of 14 subjects aged 18 to 46 years. During accommodation, the decrease in the ACD was statistically significant (P < .05), as were the increase in the lens thickness (P < .001) and the slight movement forward of the lens central point (P < .01). The CCT and anterior chamber width measurements did not change statistically significantly during accommodation. The lens thickness at 0 D was positively correlated with age (P < .01).

conclusionHigh-resolution real-time imaging and biometry of the accommodating anterior segment can be effectively performed using a commercially available swept-source AS-OCT clinical device. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.

Indexed as

Accommodation, OcularAdolescentAdultAnterior Eye SegmentBiometryFemaleHealthy VolunteersHumansMaleMiddle AgedTomography, Optical CoherenceYoung Adult

Identifiers

PMID25704218
PMCPMC4699182
OpenAlexW2014941422

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.