SynthesisJournal of psychiatry & neuroscience : JPN2015
Disadvantageous decision-making on a rodent gambling task is associated with increased motor impulsivity in a population of male rats.
Synthesis in Journal of psychiatry & neuroscience : JPN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 58 citations in OpenAlex.
- Dependence of psychopharmacological drug effects on early social stress experience: An analysis aligned with the research domain criteria framework.The Journal of pharmacology and experimental therapeutics · 2025Review
- Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in 3xTg Alzheimer's model mice.Communications biology · 2025Article
- Individual differences in training time in the rat gambling task are unrelated to subsequent decision-making strategies.Frontiers in psychiatry · 2025Article
- Noradrenergic regulation of cue-guided decision making and impulsivity is doubly dissociable across frontal brain regions.Psychopharmacology · 2024Article
- Motor impulsivity but not risk-related impulsive choice is associated to drug intake and drug-primed relapse.Frontiers in behavioral neuroscience · 2023Article
- Propensity for risky choices despite lower cue reactivity in adolescent rats.Frontiers in behavioral neuroscience · 2023Article
- Individual strategies in the rat gambling task are related to voluntary alcohol intake, but not sexual behavior, and can be modulated by naltrexone.Frontiers in psychiatry · 2022Article
- Exploring decision-making strategies in the Iowa gambling task and rat gambling task.Frontiers in behavioral neuroscience · 2022Article
- Heritable variation in locomotion, reward sensitivity and impulsive behaviors in a genetically diverse inbred mouse panel.Genes, brain, and behavior · 2021Article
- Adaptive aspects of impulsivity and interactions with effects of catecholaminergic agents in the 5-choice serial reaction time task: implications for ADHD.Psychopharmacology · 2021Article
- Sign tracking predicts suboptimal behavior in a rodent gambling task.Psychopharmacology · 2021Article
- Unilateral parietal brain injury increases risk-taking on a rat gambling task.Experimental neurology · 2020Article
- Impaired decision making following escalation of cocaine self-administration predicts vulnerability to relapse in rats.Addiction biology · 2020Article
- Translating concepts of risk and loss in rodent models of gambling and the limitations for clinical applications.Current opinion in behavioral sciences · 2020Article
- Relative insensitivity to time-out punishments induced by win-paired cues in a rat gambling task.Psychopharmacology · 2019Article
- Increased motor impulsivity in a rat gambling task during chronic ropinirole treatment: potentiation by win-paired audiovisual cues.Psychopharmacology · 2019Article
- Long-term deficits in risky decision-making after traumatic brain injury on a rat analog of the Iowa gambling task.Brain research · 2019Article
- Pharmacological evidence that 5-HTPsychopharmacology · 2017Article
- Genetic and Modeling Approaches Reveal Distinct Components of Impulsive Behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Article
- Cued Rat Gambling Task.Bio-protocol · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundImpulsivity is understood as a range of behaviours, but the association between these behaviours is not well understood. Although high motor impulsivity is a key symptom of disorders like pathological gambling and addiction, in which decision-making on laboratory tasks is compromised, there have been no clear demonstrations that choice and motor impulsivity are associated in the general population. We examined this association in a large population of rodents.
methodsWe performed a meta-analysis on behavioural data from 211 manipulation-naive male animals that performed a rodent gambling task in our laboratory between 2008 and 2012. The task measures an aspect of both impulsive decision-making and impulsive action, making it possible to evaluate whether these 2 forms of maladaptive behaviour are related.
resultsOur meta-analysis revealed that motor impulsivity was positively correlated with poor decision-making under risk. Highly motor impulsive rats were slower to adopt an advantageous choice strategy and quicker to make a choice on individual trials. LIMITATIONS: The data analyzed were limited to that produced by our laboratory and did not include data of other researchers who have used the task.
conclusionThis work may represent the first demonstration of a clear association between choice and motor impulsivity in a nonclinical population. This lends support to the common practice of studying impulsivity in nonclinical populations to gain insight into impulse control disorders and suggests that differences in impulsive behaviours between clinical and nonclinical populations may be ones of magnitude rather than ones of quality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.