ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2015
Aging and loss to follow-up among youth living with human immunodeficiency virus in the HIV Research Network.
Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Discontinuation of follow-up care for young people with complex chronic conditions: conceptual definitions and operational components.BMC health services research · 2021Pooled it
- Interruption in treatment and its risk factors among adults living with HIV in Uganda: a cross-sectional study.AIDS research and therapy · 2026Article
- Projecting lifetime HIV-related healthcare costs for youth with HIV in the United States.BMC health services research · 2025Article
- The role of general practitioners in transitioning adolescents with chronic conditions to adult health care.European journal of pediatrics · 2025Article
- Demographic and Clinical Characteristics Predicting Missed Clinic Visits among Patients Living with HIV on Antiretroviral Treatment in Kinshasa and Haut-Katanga Provinces of the Democratic Republic of Congo.Healthcare (Basel, Switzerland) · 2024Article
- Projected Life Expectancy for Adolescents With HIV in the US.JAMA health forum · 2024Article
- Adults with Perinatally Acquired HIV; Emerging Clinical Outcomes and Data Gaps.Tropical medicine and infectious disease · 2024Review
- Projecting the Clinical and Economic Impacts of Changes to HIV Care Among Adolescents and Young Adults in the United States: Lessons From the COVID-19 Pandemic.Journal of the Pediatric Infectious Diseases Society · 2024Article
- Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.PLOS global public health · 2024Article
- Article
- Challenges and Fears of Adolescents and Young Adults Living with HIV Facing Transition to Adult HIV Care.AIDS and behavior · 2023Article
- Risk factors for interruption in treatment among HIV-infected adolescence attending health care and treatment clinics in Tanzania.AIDS research and therapy · 2023Article
- Association of Perceived Social Support with Viral Suppression Among Young Adults with Perinatally-Acquired HIV in the US-based Pediatric HIV/AIDS Cohort Study (PHACS).Clinical epidemiology · 2023Article
- A Multilevel Integrated Intervention to Reduce the Impact of HIV Stigma on HIV Treatment Outcomes Among Adolescents Living With HIV in Uganda: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2022Article
- Time to Engage Young People in HIV Cure Research.AIDS research and human retroviruses · 2022Article
- Modeling Adherence Interventions Among Youth with HIV in the United States: Clinical and Economic Projections.AIDS and behavior · 2021Article
- A Mobile Health App (WYZ) for Engagement in Care and Antiretroviral Therapy Adherence Among Youth and Young Adults Living With HIV: Single-Arm Pilot Intervention Study.JMIR formative research · 2021Article
- Health care transition for patients with vascular malformations: a French multicenter cross-sectional study.Orphanet journal of rare diseases · 2021Article
- Adolescents and young adults with early acquired HIV infection in the united states: unique challenges in treatment and secondary prevention.Expert review of anti-infective therapy · 2021Review
- Ethical challenges of the healthcare transition to adult antiretroviral therapy (ART) clinics for adolescents and young people with HIV in Uganda.BMC medical ethics · 2021Article
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
Abstract
purposeIn the United States, 21 years is a critical age of legal and social transition, with changes in social programs such as public insurance coverage. Human immunodeficiency virus (HIV)-infected youth have lower adherence to care and medications and may be at risk of loss to follow-up (LTFU) at this benchmark age. We evaluated LTFU after the 22nd birthday for HIV-infected youth engaged in care. LTFU was defined as having no primary HIV visits in the year after the 22nd birthday.
methodsAll HIV-infected 21-year-olds engaged in care (2002-2011) at the HIV Research Network clinics were included. We assessed the proportion LTFU and used multivariable logistic regression to evaluate demographic and clinical characteristics associated with LTFU after the 22nd birthday. We compared LTFU at other age transitions during the adolescent/young adult years.
resultsSix hundred forty-seven 21-year-olds were engaged in care; 91 (19.8%) were LTFU in the year after turning 22 years. Receiving care at an adult versus pediatric HIV clinic (adjusted odds ratio [AOR], 2.91; 95% confidence interval [CI], 1.42-5.93), having fewer than four primary HIV visits/year (AOR, 2.72; 95% CI, 1.67-4.42), and antiretroviral therapy prescription (AOR, .50; 95% CI, .41-.60) were independently associated with LTFU. LTFU was prevalent at each age transition, with factors associated with LTFU similar to that identified for 21-year-olds.
conclusionsAlthough 19.8% of 21-year-olds at the HIV Research Network sites were LTFU after their 22nd birthday, significant proportions of youth of all ages were LTFU. Fewer than four primary HIV care visits/year, receiving care at adult clinics and not prescribed antiretroviral therapy, were associated with LTFU and may inform targeted interventions to reduce LTFU for these vulnerable patients.
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