Evidence map›Paper›PMID 25703251›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2015

Donor-derived Strongyloides stercoralis infection in solid organ transplant recipients in the United States, 2009-2013.

F A Abanyie, E B Gray, K W Delli Carpini, A Yanofsky, I McAuliffe, M Rana, P V Chin-Hong, C N Barone, J L Davis, S P Montgomery and 1 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Host genetic backgrounds: the key to determining parasite-host adaptation.Frontiers in cellular and infection microbiology · 2023
    Review
  9. Review
  10. Tropical medicine and infectious disease · 2022
    Review
  11. Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  12. Tropical Infections in the Context of Kidney Transplantation in Latin America.The American journal of tropical medicine and hygiene · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

F A AbanyieDivision of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control Prevention, Atlanta, GA.
E B Gray
K W Delli Carpini
A Yanofsky
I McAuliffe
M Rana
P V Chin-Hong
C N Barone
J L Davis
S P Montgomery
S Huprikar
Center for Global Health · USDivision of Parasitic Diseases and Malaria · USIcahn School of Medicine at Mount Sinai · USDonor Network West · USMiami Transplant Institute · USUF Health Shands Hospital · USUniversity of California, San Francisco · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Infection with Strongyloides stercoralis is typically asymptomatic in immunocompetent hosts, despite chronic infection. In contrast, immunocompromised hosts such as solid organ transplant recipients are at risk for hyperinfection syndrome and/or disseminated disease, frequently resulting in fatal outcomes. Infection in these recipients may result from reactivation of latent infection or infection through transmission from an infected donor. We describe the Centers for Disease Control and Prevention's experience with seven clusters of donor-derived infection from 2009 to 2013. Six of the seven (86%) donors were born in Latin America; donor screening was not performed prior to organ transplantation in any of these investigations. Eleven of the 20 (55%) organ recipients were symptomatic, two of whom died from complications of strongyloidiasis. We also describe the New York Organ Donor Network (NYODN) experience with targeted donor screening from 2010 to 2013. Of the 233 consented potential donors tested, 10 tested positive for Strongyloides antibody; and 18 organs were transplanted. The majority (86%) of the donors were born in Central or South America. Fourteen recipients received prophylaxis after transplantation; no recipients developed strongyloidiasis. The NYODN experience provides evidence that when targeted donor screening is performed prior to transplantation, donor-derived infection can be averted in recipients.

Indexed as

Strongyloides stercoralisTransplantationAdultAgedAnimalsCenters for Disease Control and Prevention, U.S.Donor SelectionFemaleHumansImmunocompromised HostKidney TransplantationLatin AmericaLiver TransplantationMaleMiddle AgedPostoperative Complicationsdonors and donation: donor-derived infectionsinfection and infectious agentsparasitic

Identifiers

PMID25703251
PMCPMC4747246
OpenAlexW1865331004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.